A simple synthesis of poly(ethylene glycol) methacrylate (PEGMA) coated CuInS 2 /ZnS quantum dots (QDs) has been developed. X-ray diffraction, transmission electron microscopy, and atomic force microscopy observations demonstrated that uniform CuInS 2 /ZnS QDs were successfully prepared. Fourier transform infrared spectroscopy indicated no new peak after the coating process, indicating that only physical interactions occurred during coating and that PEGMA did not disturb the crystal structure of the CuInS 2 /ZnS QDs. After PEGMA coating, the photoluminescence spectra of the CuInS 2 /ZnS QDs red shifted (from 566 nm to 589 nm) and the QD particle size increased. The concentration and molecular weight of PEGMA play important roles in the water solubility and hydrodynamics of the particles. The PEGMA-coated CuInS 2 /ZnS QDs showed stable emissions for up to 3 weeks. As a demonstration of a potential biomedical application, PEGMA-coated CuInS 2 -ZnS QDs were used in labeling human liver carcinoma (HepG2) tumor cells.
Bulleyaconitine A (BLA) (Fig. 1), a diester-diterpene type Aconitum alkaloid extracted from Aconitum longtounense T. L. MING, is a potent analgesic and anti-inflammatory agent, and can be used for the treatment of rheumatoid arthritis, osteoarthritis, periarthritis humeroscapularis, lumbar muscle strain, sprain, etc.1-3) The analgesic effect of BLA might be related to the 5-HT level in the brain, and no physical dependence has been observed. The relative analgesic effect of BLA was found to be as much as 3, 65, and 7000 times as potent as 3-acetylaconitine, morphine and aspirin, respectively.2,4) BLA has been approved by SFDA (Sino Food and Drug Administration) as intramuscular injections, tablets and soft gel capsules for clinical use in China since 1980's.The potential toxicity of the diester-diterpene type Aconitum alkaloids such as BLA is severe. The LD 50 of BLA, injected subcutaneously, is 0.92 mg/kg for mouse and 0.51 mg/kg for rat, respectively.
A method was proposed to gain three-dimensional (3D) reconstruction based on binocular view geometry. Images used to calibrate cameras and reconstruct car’s rearview mirror by image acquisition system, by calibration image, a camera's intrinsic and extrinsic parameters, projective and fundamental matrixes were drawn by Matlab7.1;the collected rearview mirror images is pretreated to draw refined laser, extracted feature points, find the very appropriate match points by epipolar geometry principle; according to the camera imaging model to calculate the coordinates of space points, display point cloud, fitting space points to reconstruct car’s rearview mirror; experimental results show this method can better restore the car’s rearview mirror of 3D information.
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