Preparation of poly(ethylene glycol) methacrylate coated CuInS2/ZnS quantum dots and their use in cell staining

Abstract

A simple synthesis of poly(ethylene glycol) methacrylate (PEGMA) coated CuInS 2 /ZnS quantum dots (QDs) has been developed. X-ray diffraction, transmission electron microscopy, and atomic force microscopy observations demonstrated that uniform CuInS 2 /ZnS QDs were successfully prepared. Fourier transform infrared spectroscopy indicated no new peak after the coating process, indicating that only physical interactions occurred during coating and that PEGMA did not disturb the crystal structure of the CuInS 2 /ZnS QDs. After PEGMA coating, the photoluminescence spectra of the CuInS 2 /ZnS QDs red shifted (from 566 nm to 589 nm) and the QD particle size increased. The concentration and molecular weight of PEGMA play important roles in the water solubility and hydrodynamics of the particles. The PEGMA-coated CuInS 2 /ZnS QDs showed stable emissions for up to 3 weeks. As a demonstration of a potential biomedical application, PEGMA-coated CuInS 2 -ZnS QDs were used in labeling human liver carcinoma (HepG2) tumor cells.

BRCAA1 antibody- and Her2 antibody-conjugated amphiphilic polymer engineered CdSe/ZnS quantum dots for targeted imaging of gastric cancer

“…In the FTIR spectrum of CdSe/ZnS QDs (Additional file 1: Figure S1b), the peak at 1,183 cm -1 is the characteristic symmetric and asymmetric stretching vibrations from TOPO ( v P=O ) [37,41]. After transferring from the hydrophobic phase to the hydrophilic phase, for PQDs (Additional file 1: Figure S1c), many peaks emerged.…”

“…The FTIR spectrum of the primary CdSe, CdSe/ZnS, and PQDs shows that (Additional file 1 : Figure S1, details of FTIR) the peak of CdSe at 2,760 ~ 2,930 cm -1 is the characteristic symmetric and asymmetric methylene stretching ( v C-H) that comes from the cosolvent material used in synthesis [ 40 ] (Additional file 1 : Figure S1a). In the FTIR spectrum of CdSe/ZnS QDs (Additional file 1 : Figure S1b), the peak at 1,183 cm -1 is the characteristic symmetric and asymmetric stretching vibrations from TOPO ( v P=O ) [ 37 , 41 ]. After transferring from the hydrophobic phase to the hydrophilic phase, for PQDs (Additional file 1 : Figure S1c), many peaks emerged.…”

Facile synthesis and photoluminescence characterization of AgInZnS hollow nanoparticles

“…Among these semiconductors, AgInS 2 has a relatively wider 2 band gap ranging from 1.87 eV to 2.03 eV, depending on its crystal structure [12][13][14][15]. For instance, ternary I-III-VI 2 semiconductor materials, such as AgInS 2 , CuInS 2 and Cu(InxGa1-x)Se 2 etc, have been widely investigated for their potential applications in photovoltaic solar cells, light emitting diodes, non-linear optical devices, photocatalytic H 2 evolution under visible light irradiation [14][15][16][17][18]. Most importantly, AgInZnS hollow structure has potential applications in photocatalystic because of its large surface area.…”

A novel strategy for the aqueous synthesis of down-/up-conversion nanocomposites for dual-modal cell imaging and drug delivery

“…From the XRD patterns shown in Fig. 3a, it can be observed that the characteristic diffraction peaks matched well with the tetragonal chalcopyrite crystal structure of ZAIS (JCPDS 85-1575) 24 and the hexagonal phase of NaYF4:Yb,Er (JCPDS 28-1192), 25,26 the XRD pattern of the UCNP/ZAIS NCs displays nearly the same pattern as pure UCNPs with a tiny diffraction peak at 2q ¼ 28 , which can be indexed to the (112) plane of ZAIS, suggesting the coexistence of ZAIS and NaYF 4 :Yb,Er NPs in the NCs. The successful attachment of QDs to the surface of UCNPs can be established through FTIR spectra and the specic recognition of carboxyl-modied NaYF 4 :Yb,Er NPs before and aer ZAIS coupling (Fig.…”