Capsaicin, a pungent alkaloid of chili pepper (Capsicum annuum) is responsible for the "hot and spicy" taste of chili. Also, Capsaicin is a pharmaceutical agent with broad therapeutic applications in controlling different diseases like diabetes, obesity, cancer, pain, and other inflammatory diseases. Capsaicin therapeutic effect is dependent on various factors like the concentration of capsaicin, delivery to different cell types, route of administration, and their metabolism. Improvement in the delivery of capsaicin will increase its therapeutic efficacy. Recent advancement in various technologies had provided numerous strategies to deliver capsaicin. This chapter outlines different strategies for using multiple new materials, formulations for the capsaicin delivery and improve their therapeutic efficacy as well their advantages and disadvantages.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.