The aim of the present study was to evaluate the expression and specific role of microRNA (miR)-142-5p in the progression of intrahepatic cholangiocarcinoma (ICC). Reverse transcription-quantitative polymerase chain reaction was performed to evaluate miR-142-5p expression in patients with ICC and healthy control subjects. The results revealed that plasma miR-142-5p was significantly increased in patients with ICC compared with the control group. Furthermore, miR-142-5p was also increased in ICC tissues compared with adjacent non-neoplastic tissues. Compared with patients with Ta-T1 stage ICC, miR-142-5p was significantly elevated in patients with ICC ≥T2 stage. Patients with ICC at G3 stage had much higher plasma miR-142-5p levels compared with those at G1/2 stage. Receiver operating characteristic analysis indicated that miR-142-5p could be used as a biomarker to differentiate patients with ICC from healthy controls. Kaplan-Meier analysis demonstrated that plasma miR-142-5p was negatively correlated with survival in patients with ICC. A dual luciferase reporter assay indicated that miR-142-5p significantly suppressed the relative luciferase activity of pmirGLO-PTEN-3' untranslated region compared with the control group. In summary, the results of the present study provide novel data indicating that plasma miR-142-5p is significantly upregulated in patients with ICC. miR-142-5p may therefore have potential as a biomarker for screening patients with ICC from healthy controls.
Abstract-Compressive sensing uses simultaneous sensing and compression to provide an efficient image acquisition technique and it has been demonstrated in optical and electrical image sensors. To guarantee exact recovery from sparse measurements, specific sensing matrix, which satisfies the Restricted Isometry Property (RIP), should be well chosen. Toeplitz-structured chaotic sensing matrix constructed by Logistic map has been proved to satisfy RIP with high probability. In this paper, we propose that chaotic sequence sampled from Colpitts oscillator can also be used to generate Toeplitzstructured chaotic sensing matrix. Simulation results show that the proposed Colpitts chaotic sensing matrix has similar performance to random matrix or other chaotic matrix for exact reconstructing compressible signals and images from fewer measurements.
With the improvement of people’s living standards, people not only to the urban landscape green space construction is satisfied with the improvement of the natural environment, but also pay more and more attention to the pursuit of urban characteristics and cultural landscape. Urban characteristic landscape should pay full attention to the natural attributes of the city, deeply integrate the landscape construction and urban characteristics with socialist civilization, and strive to establish a landscape rich in urban characteristics and humanistic themes, so as to better improve the urban value and human cultural connotation. In order to understand more about the characteristic scenic spots created by landscape art, this paper first expounds the necessity of garden landscape, the characteristics of miniature landscape and the role of plant landscape creation, explores the application method of miniature landscape effect in characteristic scenic spots, and expounds the design of an artificial landscape tree, hoping to provide reference for relevant personnel.
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