Developing safe and precise image‐guided photodynamic therapy is a challenge. In this study, the hypoxic properties of solid tumors are exploited to construct a hypoxia‐responsive photosensitizer, TPA‐Azo. Introducing the azo group into the photosensitizer TPA‐BN with aggregation‐induced emission quenches its fluorescence. When the nonfluorescent TPA‐Azo enters hypoxic tumors, it is reduced by the overexpressed azoreductase to generate a fluorescent photosensitizer TPA‐BN with an amino group that exhibits fluorescence‐activatable image‐guided photodynamic therapy with dual‐organelle (lipid droplets and lysosomes) targeting. This design strategy provides a basis for the development of fluorescence‐activatable photosensitizers.
Electrochromic power storage devices (ESCs) integrate energy storage and electrochromic behaviour into a single full cell that can enable the visualization of the energy status by the naked eye. One...
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