The reported incidence of incisional hernia after a laparotomy is 22.4% at the 3-year mark [1]. Depending on the patient's risk factors, the actual incidence of incisional hernia can be higher or lower. Patients may be asymptomatic or present with abdominal pain, discomfort, disfigurement, or bowel obstruction. The hernias can be repaired laparoscopically, robotically, or in open surgery. An open approach is generally required for large incisional hernia repairs. Possible postoperative complications following an open incisional hernia repair include wound infections, bowel obstructions, and seroma or hematoma formations. In this study, a case of an early posterior rectus sheath hernia recurrence after an open retrorectus incisional hernia repair is presented. In this case, the recurrent hernia presented with a small bowel obstruction.
Sepsis is the principal cause of hospital death among children and ranks fourth among all causes of death in infants under 1 year of age and second in 1 to 14 year old children. Objective: to assess whether activated protein C (APC) infusion may be incorporated into the complex intensive therapy for sepsis in babies of the first year of life. Subjects and meth ods. In January 2005 to April 2007, APC was used in the complex intensive therapy for sepsis in 36 infants of the first year of life. APC therapy was initiated in the first 24 hours after the occurrence of organ dysfunction in 29 (80%) patients and in the first 48 hours in others cases. Results. Status stabilization and multiple organ dysfunction (MOD) regression were noted in most patients during APC infusion. Ten (28%) patients died; mortality rates in the groups of patients with early and late infusion were 17 and 71%, respectively. The baseline APC level failed to affect 28 day survival. By the end of infusion, the mean level of protein C was much higher in the group of survivors than that in the deceased. Conclusion. APC as a part of the complex intensive therapy for sepsis should be given to infants of the first year of life who had mul tiple organ dysfunctions within the first 24 hours after the occurrence of organ dysfunction. Key words: pediatric sepsis, activated α α drotrecogin, multiple organ dysfunction.
HighlightsCoat’s plus syndrome is a rare genetic condition.Manifestations of this syndrome include ophthalmologic symptoms along with systemic manifestations such as gastrointestinal bleeding.This case report demonstrates significant morbidity and ultimately mortality associated with this condition.Further research is needed in this area to treat patients with GI bleeding in Coat’s plus syndrome.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.