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Although a trend exists towards shorter time period intervals between the first uterine visualization and distal tubal filling graphy among patients with tubal patency, rather than patients with distal tubal occlusion confirmed by diagnostic laparoscopy, clinically reliable objective time period intervals for finalizing the HSG procedure and proceeding with diagnostic laparoscopy due to distal tubal occlusion diagnosis on HSG could not be detected.

Amaç: Van Yüzüncü Yıl Üniversitesi ve Van Eğitim ve Araştırma Hastanesi'nde NTD tanısı koyulan ve sağlıklı fetüsü olan gebelerin B12 ve folat düzeyini karşılaştırdık. Gereç ve Yöntem: NTD tanısı koyulan 38 hasta ve 40 kontrol grubu çalışmaya dahil edildi. İstatistiksel analizde ki-kare testi ve Mann-Whitney U testi kullanıldı. Bulgular: NTD grubunda hiçbir hastada prekonsepsiyonel dönemde folik asit kullanımı yoktu ancak kontrol grubunda 4 (%10) hastada prekonsepsiyonel folik asit kullanımı mevcuttu ve bu fark istatistiksel olarak anlamlıydı (p=0,04). NTD grubunda 9 (%23.6), kontrol grubunda 32 (%80) hastada ilk trimesterde folik asit desteği alınmıştı ve bu istatistiksel olarak anlamlıydı (p=0,01). Ortalama B12 seviyesi NTD grubunda 248.7±65.4ng/ml, kontrol grubunda 239.3±27.5 saptandı ve bu fark anlamlı değildi (p=0,78). Ortalama folat seviyesi NTD grubunda 9.6±4.8 ng/ml, kontrol grubunda 9.8±3.9 ng/ml saptandı ve bu fark anlamlı değildi (p=0,62). Sonuç: Her iki grup arasında B12 ve folat seviyeleri farklı değildi ancak, sağlıklı bebeği olan grupta prekonsepsiyonel dönemde ve ilk trimesterde folik asit kullanımı NTD grubuna göre anlamlı olarak daha fazlaydı.

Objective: This study aimed to investigate the effect of magnesium sulfate treatment on fetal cardiac function during seizure prophylaxis of pregnant women diagnosed with severe preeclampsia and eclampsia. Fetal cardiac function was evaluated with the modified myocardial performance index (mod-MPI) before and after prophylaxis. Methods: A total of 50 pregnant women diagnosed with severe preeclampsia or eclampsia were involved. The characteristics of the participants, medical and obstetric history, ultrasound and laboratory findings were recorded. Fetal mod-MPI was obtained before and after magnesium treatment. Data were analyzed with appropriate statistical tests and p < 0.05 was considered to indicate statistical significance .Results: The mean maternal and gestational ages of pregnant women were 31.7 ± 5.9 and 32.4 ± 4.5. Mean mod-MPI before and after prophylaxis were 0.41 ± 0.18 and 0.49 ± 0.09, respectively (p<0.05). Conclusion: There was a significant increase in fetal mod-MPI after magnesium prophylaxis was given to severe preeclampctic/eclamptic women. The higher the mod-MPI, the worse the fetal cardiac function. This might have been the result of magnesium leading to an increased isovolumetric relaxation time. Key words: Preeclampsia, magnesium sulfate, myocardial performance index, eclampsia, fetus

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