The study aimed to determine the total phenol content of the extracts prepared with different solvents (70%methanol, ethyl acetate, 5% infusion) from the aerial parts of the I. oculus-christi, as well as to evaluate the antioxidant capacity and antimicrobial activity of the plant and to determine the main components responsible for the effect. The total phenolic content of the extracts prepared from the aerial parts of I. oculus-christi was calculated in gallic acid equivalents and the total phenolic content of the species was found to be in the range of 23.8-75.3 mg GAE/g. The highest total phenol content calculated as gallic acid equivalent was detected in the 5% infusion sample. The antioxidant activity of I. oculus-christi was also tested using DPPHˈ free radical scavenging in vitro assay (IC50: 0.092-1.03 mg/mL). The 5% infusion of the plant was shown to be the most effective extract in the antioxidant activity test performed using the DPPHˈ technique. The findings revealed that there is a correlation between total phenol content and antioxidant activity, as numerous research as suggested. By using the microdilution method, extracts from the aerial parts of I. oculus-christi were tested against Candida strains, and the MIC value for C. utilis was found to be 0.03 mg/mL in 5% infusion and ethyl acetate extracts. In terms of evaluating the biological effects obtained, the chemical composition of extracts was analyzed by HPLC-MS/MS, and the main components (5-caffeoylquinic acid, 1,5-dicaffeoylquinic acid, luteolin/kaempferol, apigenin, and rutin) were determined.
Tarçın, bazı Cinnamomum (Lauraceae) türlerinin gövde kabuklarından elde edilen dünyanın en eski ve sık tüketilen baharatlarından biridir. 250'nin üzerinde Cinnamomum türünden kültüre alınan ve ticareti yapılanlar Cinnamomum verum (Seylan), C. cassia (Çin), C. burmanni (Endonezya) ve C. loureiroi (Vietnam)'dir. Toz edilmiş kabukların birbirlerinden ayrılması yalnızca anatomik, morfolojik, kromatografik ve spektroskobik yöntemler ile mümkündür. Tarçın ve uçucu yağı eşsiz aromasıyla gıda, kozmetik ve ilaç sanayiinde geniş kullanıma sahiptir. Son yıllarda tıbbi amaçlarla kullanılan, özellikle diyabet hastalarına önerilen tarçının bazı türleri antikoagülan ve hepatotoksik özellikte, "kumarin" bileşiğini yüksek miktarlarda taşımaktadır. Çalışmamızda ülkemizin çeşitli illerinde satışa sunulmuş 23 adet kabuk örneği anatomik-morfolojik olarak incelenmiş, bazı örneklerin uçucu yağ kompozisyonu Gaz Kromatografisi ve Gaz Kromatografisi/Kütle Spektrometresi sistemleri ile belirlenmiştir. Yüksek Performanslı Sıvı Kromatografisi ile tüm örneklerin taşıdıkları kumarin miktarı ortaya konmuştur. Ülkemiz piyasasından temin edilen 23 tarçın örneğinin 22'sinin "cassia tip" tarçın olduğu, kumarin miktarlarının 0.042 ile 12.8 mg/gr aralığında değiştiği saptanmıştır.
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