Psoriasis (Kitibha) is one of the most common chronic skin disorders, which has psychological and social impact on patient’s life. This disease is not contagious and may affect people of any age, but it commonly begins around 15 to 40 years. Psoriasis is commonly red and white hues of scaly patches appearing on the top of skin. This disease is equated to Kitibha in Ayurveda due to its invariable similarities in signs and symptoms. This case study aims to investigate whether Ayurvedic intervention can manage moderate to severe Psoriasis (Kitibha). A 41‑year old male came to the Outpatient Department (OPD) of Central Ayurveda Research Institute, Guwahati with clinical features indicative of Psoriasis. This case was diagnosed as Kitibha and was managed by Ayurvedic interventions of Kaishore Guggulu 1gm twice a day, Arogyavardhini vati 500mg twice a day, Panchtiktaguggulu Ghrit 3 gm twice a day and Brihat Marichyadi tail local application twice a day for 3 months at OPD level. The response to the treatment was found to be highly effective. At the end of the treatment period and follow up of 1 month as compared with baseline, highly significant changes were observed. Kaishore Guggulu, Arogyavardhini vati, Panchtiktaguggulu Ghrit and Brihat marichyadi tail in the above‑mentioned doses were found to be very effective and safe in moderate to severe case of Psoriasis (Kitibha).
Introduction: Ayurvedic interventions have been in practice for treatment of thyroid-related disorders alone or in combination with complementary medicine. No systematic review has been conducted for assessing the efficacy and safety of Ayurvedic intervention in hypothyroidism. Present study aimed to provide quality evidence to assess for the efficacy and safety of Ayurveda interventions for hypothyroidism in the 18-60 years' age-group. Materials and methods: For collection of data, all research article based on randomized controlled trials, multiple-arm clinical trials, nonrandomized clinical trial, quasi-randomized controlled trials having intervention period of at least 12 weeks' duration will be considered and searched from inception to September 2019 in several databases. Primary outcome will include response to treatment (improvement in subjective criteria of assessment, i.e., hypothyroidism-related symptoms), effect on values of laboratory measures related to thyroid gland functioning like tri-iodothyronine (T3), tetra-iodothyronine (T4), and thyroid-stimulating hormone (TSH) and serious adverse events. Secondary outcome will include measurement of health-related quality of life. Data extraction will be done independently by three reviewers in a predefined format. A narrative synthesis will be conducted for all included study. If extracted data will be eligible for meta-analysis, a meta-analysis will be conducted. Ethics and dissemination: This review does not require formal ethical assessment and approval, as no confidential participant data will be included. Findings will be disseminated widely through publication, conference, and symposia.
Desmodium gangeticum (L.) DC., commonly known as Shalparni in Ayurveda, has been used for treating various diseases. The plant is one among ten ingredients of classical Ayurvedic formulations Dasamula. Decoctions of root and leaf, root powder and leaf juice of D. gangeticum are used as tonics, febrifuge, digestive, antiemetic, astringent, anti-asthmatic, anti-diarrhoeal and anti-inflammatory agents in traditional medicinal practices of India and its neighbouring countries. Phytochemical investigations of this plant revealed the presence of many bioactive phytoconstituents. The present review was prepared with the objective of documenting the phytochemical and pharmacological profiles of D. gangeticum. The data presented here were collected from various sources like books, journals, various online databases, and monographs and internet search engines Google Scholar, PubMed, Science Direct, etc. Studies reported from phytochemical screening revealed that D. Gangeticum leaves and roots are rich in flavonoids, alkaloids, terpenoids, tannins, phenols, carbohydrates, steroids, phenylpropanoids, pterocarpans, coumarins, and volatile oil. Among the isolated compounds, major bio-active constituents are alkaloids, flavonoids and pterocarpans. All these phytochemicals are widely distributed in various parts of D. gangeticum. The other active constituents like desmodin, hordenine and gangetin are largely responsible for its broad spectrum of therapeutic potentiality. Desmodin belongs to the class of pterocarpans and is reported to have antifungal and antibacterial activities. Gangetin, which also belongs to the pterocarpans, is reported to have anti-inflammatory and analgesic effects. FTIR spectroscopy showed that D. gangeticum extracts are mainly rich in phenolic derivatives. Scientific experiments carried out in vitro as well as preclinical animal experimentations, showed that the plant and its bioactive chemicals exhibit various therapeutic activities. It is reported that D. gangeticum extracts showed potent antioxidant, antibacterial, hypoglycaemic, analgesic, hepatoprotective, anti-inflammatory and antiarthritic activities. Studies reported that D. gangeticum or its formulations are safe when used in appropriate therapeutic dosage.
Diabetes Mellitus is a metabolic disorder associated with multisystem complications. The prevalence and incidences of the both types of diabetes are significantly increased over the past two decades. The recently published ICMR-INDIAB national study reported that there are 62.4 million people with type 2 diabetes mellitus and 77 million people with prediabetes in India. These numbers are projected to increase to 101 million by the year 2030 due to changed of life style of the people all over the world. Habits of sedentary life, having a lot of fast foods and improper follow of diet habits are the main causes to develop Diabetes mellitus. It can be correlated with Madhumeha in Ayurveda. A 45 years old female patient treated in the OPD of Central Ayurveda Research Institute, Guwahati from 23rd Sept. 2020 with a complain of generalised weakness, weight loss, increase amount of urination and attraction of ant towards the excreted urine for 9 months. Examination, laboratory investigations and history leads to diabetes mellitus. Different Ayurvedic herbomineral drugs which were mentioned in different texts were given to the patient. It shows the effective results in the management of Madhumeha (Diabetes mellitus).
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