The object of this study concentrated on investigating the antimicrobial susceptibilities of Ureaplasma parvum isolates to determine the most suitable antibiotic for treating the infection. In total, 35 samples of Ureaplasma parvum isolates were included in this study. Antibiotic susceptibility was studied by broth dilution method which was for the purpose of susceptibility testing of serovar isolates of Ureaplasma parvum against eight antibiotics. The results revealed the serovar 3 isolates were fully resistant (100%) to gentamicin, azithromycin and erythromycin while susceptible at the rates of 80% to doxycycline, 60% to levofloxacin and 60% to clarithromycin. Serovar 14 isolate was revealed fully susceptible (100%) to clarithromycin, ciprofloxacin and doxycycline, while fully resistant (100%) to gentamicin and azithromycin. Serovar 1 and serovar 6 were showed to be fully resistant (100%) to azithromycin and gentamicin. Sevorar 1 was susceptible to at the rates of 70% to doxycycline, 60% to tetracycline, 90% to ciprofloxacin, 70% to levofloxacin, 70% to erythromycin and 70% to clarithromycin. Serovar 6 was susceptible at the rates of 80% to doxycycline, 100% to tetracycline, 100% to ciprofloxacin, 80% to levofloxacin, 80% to erythromycin and 80% to clarithromycin. These results evidently demonstrated that doxycycline, clarithromycin and levofloxacin should be the preferred drug when empirical treatment was required.
The objectives of this study were to investigate the occurrence of Ureaplasma parvum in women with recurrent abortion and to determine the distribution of U. parvum serovars (1, 3, 6, 14) in women with recurrent abortion by conventional PCR technique. In total, 130 samples including vaginal bleeding, vaginal swab, and urine were collected from women with recurrent abortion and 40 samples including vaginal swab and urine from control women without recurrent abortion. Through the study, two types of media were used, Ureaplasma broth (IH Broth) and Ureaplasma agar (IH Agar). The positive isolates for Ureaplasma spp. were investigated by conventional PCR technique for identification of U. parvum and subtyping to their serovars (1, 3, 6, 14). The results revealed the U. parvum was identified in 29.6% from the patient group and 11% from the control group. U. parvum isolates were further subtyped using PCR, the results showed that serovar 3 was the most frequent isolate in a proportion of 42.8%, with serovar 1 (28.5%), serovar 6 (14.2%), and serovar 14 (14.2%) in the patient group, but in the control group only serovar 1 was isolated in a proportion of 11%. These results evidently indicate that U. parvum may be an important etiologic agent for recurrent abortion.
The objects of study is concerted to investigate the occurrence of Ureaplasma parvum in women with recurrent abortion and to determine the distribution of U. parvum serovars (1,3,6,14) in women with recurrent abortion by conventional polymerase chain reaction (PCR) technique. In total, 130 samples included vaginal bleeding, vaginal swab, and urine, were collected from women with recurrent abortion and 40 samples included vaginal swab and urine from control women without recurrent abortion. Through the study, two types of media were used, Ureaplasma broth (IH Broth) and Ureaplasma agar (IH Agar). The positive isolates for Ureaplasma spp. were investigated by conventional PCR technique for identification of U. parvum and subtyping to their serovars (1,3,6,14). The results revealed the U. parvum was identified in 29.6% from patient group and 11% from the control group. U. parvum isolates were further subtyped by using PCR, the results showed the serovar 3 was the most frequent isolate in proportion (42.8%), whereas serovar 1 (28.5%), serovar 6 (14.2%), and serovar 14 (14.2%) in patient group but in the control group only serovar 1 was isolated in rate (11%). These results evidently indicate that U. parvum may be an important etiologic agent for recurrent abortion.
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