Susceptibility and Antimicrobial Resistance of Genital Ureaplasma Parvum

Abstract

The object of this study concentrated on investigating the antimicrobial susceptibilities of Ureaplasma parvum isolates to determine the most suitable antibiotic for treating the infection. In total, 35 samples of Ureaplasma parvum isolates were included in this study. Antibiotic susceptibility was studied by broth dilution method which was for the purpose of susceptibility testing of serovar isolates of Ureaplasma parvum against eight antibiotics. The results revealed the serovar 3 isolates were fully resistant (100%) to gentamicin, azithromycin and erythromycin while susceptible at the rates of 80% to doxycycline, 60% to levofloxacin and 60% to clarithromycin. Serovar 14 isolate was revealed fully susceptible (100%) to clarithromycin, ciprofloxacin and doxycycline, while fully resistant (100%) to gentamicin and azithromycin. Serovar 1 and serovar 6 were showed to be fully resistant (100%) to azithromycin and gentamicin. Sevorar 1 was susceptible to at the rates of 70% to doxycycline, 60% to tetracycline, 90% to ciprofloxacin, 70% to levofloxacin, 70% to erythromycin and 70% to clarithromycin. Serovar 6 was susceptible at the rates of 80% to doxycycline, 100% to tetracycline, 100% to ciprofloxacin, 80% to levofloxacin, 80% to erythromycin and 80% to clarithromycin. These results evidently demonstrated that doxycycline, clarithromycin and levofloxacin should be the preferred drug when empirical treatment was required.