Most of the problems encountered were logistic in nature. Early evacuation of the victims remains pivotal in saving lives. The major causes of death in peripheral patients was hypovolemic shock, sepsis, and hypothermia. Mortality and morbidity can be enhanced by ample fluid resuscitation, tetanus prophylaxis, and proficient first aid at the site of injury.
Objective: To determine the efficacy and safety of stepwise oral misoprostol with vaginal misoprostol for cervical ripening for induction of labour. Study design: Interventional Quasi - Experimental study. Setting and duration: The study was of 15 months (April to 30 June) duration conducted at Obstetrics and Gynaecology department Military Hospital Rawalpindi. Subjects and methods: 100 females between 37-42 weeks of gestation were randomly divided into two groups 1and 2. Patients in group -1 assigned to the stepwise oral misoprostol arm received 50 μg initially followed by 100 μg every 04 hours upto maximum 04 doses ; group-2 assigned to the vaginal misoprostol arm received 25 μg every 04 hours up to maximum 04 doses. Subsequent doses of misoprostol were withheld if adequate uterine activity (≥3 contractions in 10 minutes) or a Bishop score ≥ 8 had been achieved, or active labour had begun. The main outcomes were the interval from first misoprostol dose to delivery and mode of delivery. Patients were also monitored for adverse events. Results: There was no difference in the average interval from the first dose of misoprostol to delivery in the oral (21.1 ± 7.9 hrs) and vaginal (21.5 ±11.0 hrs, p = NS) misoprostol groups. 9 patients in the oral group (18%) and 16 patients in the vaginal group (32%) underwent caesarean section (p<0.05). There were no significant differences in the occurrence of tachysystole, hypertonus, hyperstimulation or neonatal outcome between two groups. Conclusions: Oral misoprostol appears to be as effective as vaginal misoprostol for cervical ripening with a low incidence of hyperstimulation, no increase in side effects, and is associated with a lower cesarean section rate.
Acute appendicitis is a diagnostic dilemma in young female patients. Ultrasonography has an important role in making preoperative diagnosis and ruling out other gynecological pathologies in women. Objectives: (1) To determine the diagnostic accuracy of ultrasonography for acute appendicitis. (2) To compare it with impression, in female patients. Design: Cross-sectional comparative study. Setting: Female Surgical department. Combined Hospital, Rawalpindi. Period: Mar 2006 - Jun 2008. Patients and Methods: 214 consecutive female patients presenting with pain right lower abdomen were enrolled. The patients were assessed clinically. Blood complete picture and urine analysis was carried out in all patients. Ultrasonography was performed by radiologist with 7.5 MMz short-focused high-resolution probes. Patients were operated upon and appendicectomy was done. Specimens were sent for histopathology to confirm appendicitis. Results: Ultrasound supported the diagnosis of acute appendicitis in 163 (76.2%) patients. In ultrasound with positive findings, patients 161 (98.8%) had inflamed appendices on histopathology and 2 (1.2%) had normal appendices. The over all sensitivity of ultrasonography was 81.3% and specificity was 87.5%. Diagnostic accuracy of ultrasonography was 81.8%. The over all sensitivity of surgeon’s clinical impression remained81.8% and specificity was 62.5%. Diagnostic accuracy of ultrasonography was 81.8%. Conclusions: Ultrasound should be the initial diagnostic modality in females presenting with right lower abdominal pain. It is highly specific, effectively rules out other pathologies and helps in minimizing the avoidable surgical trauma.
Authors' Contribution GN and KT conducted the research and compiled the results. AH analyzed the data and wrote the manuscript. MR critically reviewed the article. SA supervised the study.
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