A case-control study investigated the association between dietary fat and breast cancer in Saudi Arabian women attending a specialist hospital in Riyadh. Women with breast carcinoma [n= 499] newly diagnosed between 1996-2002, and control women [n = 498] randomly selected from patients’ attendants and relatives, completed a food frequency questionnaire. Serum levels of triglycerides and total cholesterol were measured. A significant positive association was found between risk of breast cancer and intake of fats, protein and calories. Adjusted odds ratios for the highest quartile of intake versus the lowest were 2.43 for saturated fat, 2.25 for animal protein, 2.12 for polyunsaturated fat, 1.88 for cholesterol and 2.69 for total energy from dietary intake. For serum triglycerides the adjusted odds ratio was 2.16 for the highest quartile

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http://eajbsf.journals.ekb.eg/ Toxicity of Nanosilica Particles on Eobania vermiculata and Their Effects on Biochemical Changes in Rats.

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The current study aimed to evaluated the toxicity of Abrus precatorius (AP) and Ricinus communis (RC) plants on land snail (Theba pisana) and their effects on biochemical and histological changes in brown rat (Rattus norvegicus). Different concentration (1%, 1.5%, 2% and 2.5%) of AP and RC were used in this study to evluate their effects. The findings of this study pertained that the seeds of AP and RC had potential impact to control T. pisana and the LC50 of AP and RC had negative effects on many life cycle stages of T. pisana. The oviposition and new generation of T. pisana decreased by 81.2% and 62.5% and by 100% and 96.7%, while the infertility rate declined by 96.4% and 82.4% after treating T. pisana by AP and RC, respectively. Results also showed that AP and RC had weak influences on the liver, spleen, intestine, kidney and testis tissues of R. norvegicus. Furthermore, the effect was relatively higher for A. precatorius than R. communis on R. norvegicus males.