Although the hippocampal theta rhythm is thought to be linked to memory processes, its mechanism of action is unknown. Furthermore, the hippocampus forms strong connections with a functionally similar structure, the medial prefrontal cortex (mPFC). The midline thalamus appears to be an intermediate between these two structures. We recorded neurons of a midline nucleus (nucleus reuniens, RE) during theta and non-theta states. Additionally, we recorded hippocampal CA1 population responses to RE stimulation. RE cell firing patterns are classified as (i) spike rate response to stimulation (ii) determination of bursting events (iii) coherence estimation between hippocampal EEG and RE response to stimulation (within the theta frequency band of 5 - 12 Hz). The present data suggests an increase in RE spike rate due to tail pinch elicited theta activity, with no evidence of bursting activity and a weak coherence within the theta band. Furthermore, we evaluated evoked excitatory post-synaptic potentials (EPSPs) in the hippocampal CA1 to RE stimulation, as well as entorhinal cortex (EC) stimulation. We demonstrated a consistent reduction in evoked potential (EP) latency at CA1 to RE and EC stimulation during theta compared to non-theta states.
In a recent report, the Commission for Evidence-Based Policymaking advocated for expanded use of data, including data linkage, from federal statistical and regulatory agencies to help guide decision-making and ultimately improve programs and policies. How data sharing and linkage is framed is important, and attitudes about data sharing and linkage are driven by respondents’ privacy beliefs and views towards the government more generally. Using data from the RDD telephone Gallup Daily Tracking Survey, we examine how favorability towards data sharing for the purpose of informed decision-making compares to other purposes. Respondents were less favorable towards data sharing when the purpose was for informed decision-making than for efficient use of taxpayer money, government accountability, or for community benefits, suggesting this is an ineffective way to frame data sharing to increase support. However, views towards the government, beliefs about privacy, and response behavior are still important determinants of favorability.
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