Chronobiology (from chronos , time; bios , life; and logos , science) investigates the mechanisms underlying variability in the otherwise unassessed physiological range, including rhythms found in us, resonating with cycles around us. Broad time structures (chronomes) consisting of deterministic chaos and trends organized by rhythms are found in organisms and in their environments. They are mapped by chronomics as the reference values for both an applied chronomedicine and a basic chronobiology. Chronomics quantify health, identifying new disease risks, diagnosing predisease and overt illness, enabling timely and timed treatment ( R x ), and validating the short‐ and long‐term efficacy of a given R x on an inferential statistical individualized (as well as population) basis.
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