Background The etiology of Dupuytren's disease is unknown, and the role of occupational exposure is still debated. Our objective was to study the association between occupational exposures, personal risk factors and Dupuytren's disease. Methods In this cross‐sectional survey, nine occupational physicians performed clinical examinations, focused on Dupuytren's disease, of 2,406 French male civil servants employed at the Equipment Ministry in 1998 and interviewed them about medical history, leisure manual exposure and occupational biomechanical exposure to vibrations and manual work. A cumulative occupational exposure score was defined, with three levels of exposure. Results Dupuytren's disease was diagnosed in 212 men (8.8%). The occupational exposure score was significantly higher in this group of cases than in the rest of the sample (377 (SD280) vs. 223 (SD250), respectively; P < 0.0001). Occupational exposure was associated with Dupuytren's disease (adjusted Odds Ratio = 2.20 [1.39–3.45] for the intermediate and 3.10 [1.99–4.84] for the high exposure groups), with adjustment for age, leisure physical activities, alcohol consumption (≥5 servings per day), history of diabetes, epilepsy, hand trauma, and familial history of Dupuytren's disease. Conclusion Manual work exposure was associated with Dupuytren's disease after adjustment for personal risk factors. Longitudinal studies are needed to confirm these results. Am. J. Ind. Med. 51:9–15, 2008. © 2007 Wiley‐Liss, Inc.

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Objective To study acute poisoning in Sri Lankan children.Design A prospective hospital based study.Setting Lady

This is a retrospective study of 354 suspected cases of dengue haemorrhagic fever (DHF), admitted to Lady Ridgeway Hospital (LRH), Colombo during 1996. The objective of the study was to determine the correlation between clinical, laboratory, radiological and serological diagnosis of DHF. Diagnosis was based on the haemagglutination inhibition test. Serologically, 177 cases had dengue infection and, of these, 143 children had DHF. There was only a 50% correlation between clinical suspicion of DHF and positive serology. There was 100% correlation between laboratory and radiological diagnosis of DHF and positive serology.

This is a prospective hospital based study of 526 cases of kerosene oil poisoning seen during a 10 year period. There were 5 cases of deliberate self poisoning and 1 case of attempted homicide. 520 cases were accidental. Pneumonitis occurred in 299 children of whom 253 had vomited after kerosene oil ingestion. There were 3 deaths.

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A prospective study was carried out on 101 neonates with jaundice due to ABO incompatibility. The direct Coomb's test was weakly positive in 4 cases. The indirect Coomb's test using the eluate was positive in 8 cases. In the maternal blood either IgG anti-A or anti-B haemolysin was present in high titre in every case. Phototherapy was given when the indirect serum bilirubin level exceeded 9 mg/dl. Exchange transfusion was done-in 39 cases, 9 babies requiring multiple exchanges. There were 2 deaths.