d) Seventy per cent using metric. Number increasing. The younger men are more inclined to use metric.It would seem that some small progress has been made.Further progress can be developed by employing the metric system whenever possible, especially in teaching centers and during the preparation of papers for publication, and by the adoption of this system of dosage by drug manufacturers. Apparently the use of this system would not be objected to by official bodies, regulatory or otherwise. The universal use of the metric system in scientific work, its adoption for general purposes in many countries and its practical simplicity have always been sound reasons for the use of the metric system in medicine. The immediate and practical stimulus to the Council in deciding to adopt the metric system exclusively in its publications has been the occurrence of serious accidents in dosage due to confusion between the two systems. The Council particularly would like the cooperation of teachers and students in our medical schools and of the firms making pharmaceuticals and biologicals in using the metric system. It would like to invite its engineering colleagues to consider an equivalent step. The universal adoption of the metric system would be a manifestation of rationality and of interprofessional and international cooperation of high practical utility.
NEW AND NONOFFICIAL REMEDIESDIODOQUIN.-S^-Diodo-S-hydroxyquinoline, CrLN.OH. I2.-A compound resulting from the introduction of two atoms of iodine into 8-hydroxyquinoline. Í OH Actions and Uses.-Diodoquin is proposed as an antiprotozoan agent for use in amebic dysentery and in the treatment of Trichomonas hominis (intestinalis) infections.Dosage.--Adults-seven to ten tablets a day for fifteen to twenty days.Tests and Standards.-Diodoquin occurs as a yellowish brown, practically odorless powder. It is almost insoluble in water, sparingly soluble in alcohol, ether and acetone, soluble in hot pyridine and in hot dioxane. Diodoquin melts between 200 and 215 C. with extensive decomposition.Warm a few crystals of diodoquin with 1 cc. of concentrated sulfuric acid: vapors of iodine are evolved. Heat 0.5 Gm. of diodoquin mixed with 5 Gm. of anhydrous sodium carbonate in a deep crucible; cool; extract the mixture in 10 cc. of water; acidify with diluted nitric acid.Filter and add 13 cc. of tenth-normal silver nitrate solution to the filtrate. Shake to coagulate the precipitate and filter. Add 1 cc. of tenth-normal silver nitrate solution to the filtrate, shake and filter through a fresh filter paper. -Wash the precipitate on the filter: a yellow^c olor is observed (distinction from vioform, which gives a zvhite precipitate).Dry 1 Gm. of diodoquin over phosphorus pentoxide for twenty-four hours: the loss in weight is less than 0.1 per cent. Incinerate about 1 Gm. of diodoquin: the ash is not over 0.5 per cent.Mix about 0.15 Gm, of diodoquin, accurately weighed, in a nickel crucible with 5 Gm. of anhydrous potassium carbonate (or sodium carbonate). Mix thoroughly with a dry stirring ro...
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