The toxicity of a series of esters of acrylic and methacrylic acids was determined in groups of mice, and the resultant LD50 values were analyzed with the use of the mathematical models of Free and Wilson and of Hansch to relate structure of the compounds to toxicity. Both models proved valuable in relating structures to toxicity parameters, but the more useful method for predicting toxicity was the Hansch model.

possibility data in the region of low 1 / V must be available to determine the intercept precisely. This was not the case for 3-methylpentane, since the lowest density (1/ V) measured was 3.2 gram moles/liter at pressures of 41 and 55 atm., respectively.A certain amount of scatter was found when the reduced third virial coefficients for the isomeric hexanes were plotted against reduced temperature (Figure 2). This result was not surprising, since DaVid and Hamann (2) had found about the same degree of scatter (except the 'deviation of the 3-methylpentane points) for varied data in determining the solid line of Figure 2.Here again the greater deviation of the 3-methylpentane data is probably due to lack of low density compressibility data. NOMENCLATURE B = second virial coefficient, liter

No abstract

No abstract