These results indicate that 7 d of dietary nitrate supplementation enhanced the in vivo contractile properties of the human skeletal muscle. Specifically, nitrate supplementation improved excitation-contraction coupling at low frequencies of stimulation and enhanced evoked explosive force production but did not affect maximum or explosive voluntary force production in untrained individuals.
A 6-year-old neutered female domestic shorthair cat weighing 3.1 kg was referred to the clinic owing to a 2 day history of anorexia. On physical examination, a pectus excavatum (PE) was apparent, and a cranial abdominal mass was palpated. Serum biochemical analysis showed severely elevated liver enzymes. On radiography, the PE was graded as moderate, and a 5 × 3 cm soft tissue density mass was detected in the cranial abdomen. Using duplex ultrasonography, the mass was identified as an enlarged liver lobe with vascular thrombosis. The diagnosis of liver lobe torsion (LLT) was confirmed surgically, and the affected left lateral lobe was resected. On follow-up, performed 1 and 6 months postoperatively, no further abnormalities were found on clinical examination or serum biochemical analysis. At follow-up examination, the PE did not appear to cause any additional clinical signs, indicating that treatment of moderate PE in older animals is not obligatory. This is the first reported case of LLT with concurrent PE, and the second feline case of LLT treated surgically. Animals with anatomical malformation of the diaphragm caused by PE may be at higher risk of developing LLT. Early diagnosis and surgical intervention of LLT can produce a good clinical outcome without further repercussions.
Objectives The aim of this study was to report complications, as well as short- and long-term clinical outcomes of cats suffering from surgically reduced intussusception with and without enteroplication. Methods Medical records of cats presented at our institution with intussusception between 2001 and 2016 were reviewed. The following data were retrieved: signalment; history; physical examination; diagnostic imaging, surgical and histological findings; and outcomes. Animals were grouped as with or without enteroplication. Duration of surgery, survival, complication and recurrence rates, duration of hospitalisation, and short- and long-term outcomes were compared. Results Cats with intussusception presented with unspecific type and duration of clinical signs. Male or male castrated cats and Maine Coons were over-represented in both groups. Enteroplication was performed in 48% (10/21) of the cats. Cats in the enteroplication group were significantly younger than those in the non-enteroplication group ( P = 0.023). Duration of surgery, time of hospitalisation, complication rate and outcomes did not differ between the two groups. Two complications in the short term and one complication in the long term were possibly associated with enteroplication. A recurrence of intussusception was seen in 2/17 cats approximately 12 months after initial surgery, both previously treated with enteroplication. Conclusions and relevance Although the number of cases was limited, our results suggest that enteroplication should be cautiously performed in cats with intussusception as it may be associated with major complications in the short and long term, and its efficacy remains unclear. Based on this study, the need for enteroplication in cats following a correction of intussusception could be questioned.
ObjectiveTo identify phenotypic parameters correlating with the inner tracheal diameter (ITD) and endotracheal tube size (ETS) in adult dogs and to develop a chart for ETS estimation.MethodsFive-hundred and forty-four adult dogs; 100 dogs were enrolled prospectively and 444 dogs retrospectively. Different phenotypic parameters, the ITD on latero-lateral radiography and ETS were prospectively measured in dogs that underwent general anaesthesia. The parameter correlated best with the ITD was used to develop a graphic chart for ETS estimation. The accuracy of this chart was then retrospectively tested.ResultsIn prospective cohort, the correlation between body size and body mass and ITD (r=0.85 and r=0.84) was good, and the highest correlation observed between ETS and body mass (rs=0.92, P<0.001). In the retrospective assessment, the mean difference between the predicted and used ETS was 0.0 (sd±0.84) for mesocephalic/dolicocephalic (MDC) dogs, showing high accuracy, but for brachycephalic dogs, it was 1.3 (sd±0.98).ConclusionA graphic chart for ETS selection in dogs, using body mass, was designed in this study and was demonstrated to be accurate for ETS prediction in MDC dogs but not in brachycephalic dogs.
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