Four different "club drugs" are reviewed: MDMA (methylenedioxymethamphetamine, "Ecstasy"), GHB (gamma-hydroxybutyrate), ketamine, and Rohypnol (flunitrazepam). The neurobiology, clinical pharmacology, and treatment issues for each are discussed.

This article reviews research that has used the Brazelton Neonatal Behavioral Assessment Scale (NBAS; Brazelton, 1984) as an intervention. It discusses separately the various effects NBAS intervention has been found to have in areas such as parent‐infant interaction, infant development, temperament, and parental attitudes and satisfaction. Inconsistent findings are noted in each of these areas. This article then addresses issues that may play a role in the effectiveness of NBAS intervention, including the risk status of the population, the intensity of the intervention, and the receptivity of the parent. It concludes by suggesting that realistic goals be set concerning the expectations for early, short‐term intervention such as the NBAS.

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Drug-exposed infants did not differ from nonexposed infants on Neonatal Behavioral Assessment Scale (NBAS) clusters or on birth characteristics. Infants (n = 137) born to three groups of low-income mothers--cocaine and poly-drug-using mothers in a drug user treatment group (n = 76) and in a treatment rejecter group (n = 18), and to a nonuser group (n = 43)--were examined at 2 days and 2-4 weeks. The motor cluster improved and regulation of state worsened from time 1 to 2. There were no interactions of group by time. Regression analyses were conducted to see whether group differences might either emerge or disappear after removing effects of competing variables, but they did not. Power analysis showed that sample size was sufficient to have detected group differences.

We review the effects of maternal cocaine use on the developing human fetus and infant in terms ofWhile many infants show no ill effects from cocaine use by their mothers, deleterious consequences appear for some prenatally exposed infants. Biological insult has been shown in a wide variety of studies, tAssociate Professor,