Tendon lesions have a great effect on the quality of life and medical spending. Thus is important to investigate the mechanisms responsible for tendon healing and to identify novel treatment options. The aim of the present study was to evaluate the effect of Selenium on the healing processes of injured tendons. A total of 20 Wistar male rats were used and were split into two groups with two different treatment methods. The first group received a normal food administration, while the second group received Na 2 SeO 3 . The animals were kept for 28 days. During the eighth day, all animals underwent surgical experimental Achilles tendon lesion and a Kessler-type suture. After three weeks, the animals were sacrificed and the tendon was extracted for histological evaluation in order to do a comparison according to the Movin scale (modified by Bonar). The histological evaluation revealed an even orientation of the collagen fibers in the case of the experimental group (Se) compared with the second group. The Bonar score was 1.62 for the Se group, while the control group had a Bonar score of 1.98. The average number of tenocytes in the Se group was lower which is demonstrated by a lower Bonar score (1.22), compared with the second group (Bonar Score 1.85). In addition, a slightly higher number of tenocytes compared with the intact tendon areas was recorded. In vascularization, a decreased amount of blood vessels in the experimental group (Se) was observed (Bonar Score 1.70), compared with the control group (Bonar score 1.96). The present study demonstrated that Selenium administration on murine models could be beneficial for tendon healing. Further clinical research is required in order for this to be confidently recommended.
The electrocardiogram (ECG) is a graphical recording of the cardiac electric activity during cardiac revolutions. This bio-current triggers and maintains the mechanical activity of the heart. Within this research, the amplitudes values of the electrocardiographic waves were determined in 6 leads: I, II, III, aVL, aVR and aVF. Thus, some electrocardiograms were recorded using limb lead in clinically healthy kids, aged 1 month, 3 months and 5 months, in order to achieve the proposed objectives. Then, the statistical analysis of the obtained results was performed using t (student) test.As a consequence of the interpretation of the obtained results, it was noticed that the limb leads can be used successfully for recording the electrocardiogram in kids because it provides an easy aspect to interpret. The highest amplitude of the electrocardiographic waves is recorded in I lead, in the case of the 1 month old kids (having the following values: 0.115 mV ± 0.010 for P wave; 0.625 mV ± 0.078 for QRS complex; 0.460 mV ± 0.045 for T wave) and in II lead (having the following values for the 3 months old kids: 0.071 mV ± 0.015 for P wave; 0.540 mV ± 0.064 for QRS complex; 0.310 mV ± 0.052 for T wave and having the following values for the 5 months old kids: 0.071 mV ± 0.015 for P wave; 0.455 mV ± 0.028 for QRS complex; 0.430 mV ± 0.026 for T wave). It also found that the lowest amplitude of electrocardiographic waves is recorded in the aVF lead, but this lead cannot be used for ECG recording in kids.
Cadmium’s mechanism of toxicity is manifested by its fixation in mitochondria, inhibition of cellular respiration and oxidative phosphorylation. Vitamin E could act as a protective factor against the harmful effect of Cadmium intoxication. The experimental animals were randomly allocated into 3 experimental groups of 6 rats. The collected blood samples were used to determine hematocrit, hemoglobin concentration, blood erythrocyte count and leukocyte count. The following derived red blood cell parameters were calculated in parallel according to the standard methodology. Between groups 1 and 2 there are no significant differences, a sign that vitamin E exerts an effective protective role. We found a significant increase in the white blood cell count and the neutrophil count in group 3 compared to group 1. Between groups 1 and 2 there are no significant differences, a sign that vitamin E has annihilated the cadmium-induced specific effect. In the case of cadmium poisoned rats, we found a decrease in the number of red blood cells, the hematocrit and the hemoglobin level, but also a significant increase in the number of white blood cells. If rats were treated with cadmium and vitamin E, there were not significant differences from the control group.
Animal stress is a current topic intensely addressed. The general adaptation syndrome, following short exposure to stressors with low or medium intensity, has a positive effect, inducing eustress and improving adaptive capacity. Exposure to strong stressors or over a long period of time has the effect of inducing distress. The aim was to evaluate the stressful effect they have on horses, the specific activities of equine-assisted therapy, in the case of children with autism spectrum disorders. Were used 10 riding horses (8 females and 2 males), of purebred English breed, divided into 2 groups, aged between 4-8 years. The animals had the same maintenance conditions and lifestyle. Samples were taken from the jugular vein in 5 ml heparinized tubes. The parameters were determined using a ProCyte Dx Hematology Analyzer. The data obtained were statistically analyzed, calculating the Mean and Standard Deviation (Microsoft Excel). The results show that the specific activities of equine-assisted therapy do not have a stressful effect on the pathways used. These activities were less stressful than regular recreational riding activities in a riding school, subjecting the animal to less intense physical exertion than daily activities.
Nowadays, a high incidence of cutaneous tumors is observed in domestic carnivorous in pet clinic, the sebaceous glands being the starting point for the development of these tumors. The hormonal imbalances are considered to be the most common etiology for these tumors, so the current research is based on the effects of an androgenic like hormonal drug on the functionality of the sebaceous glands in dogs. For this purpose, 32 dogs were distributed in 4 groups: control group 1 (8 dogs -females), control group 2 (8 dogs -males), experimental group 1 (8 dogs -females) and experimental group 2 (8 dogs -males).The investigation targeted the pH of skin and the rate of sebum's secretion. The animals from the experimental groups were treated with Anabolin forte for 2 days at a dose of 1 mg/kg body weight/day, intramuscular.The obtained results revealed that administration of Anabolin forte in males induced a significantly distinct intensification (with 10.66%) of sebum's secretion and a significant decrease of pH of the skin (with 17.1%) compared to the animals from the control group. The administration of Anabolin forte in females induced a significantly distinct intensification (with 17.47%) of sebum's secretion and a significant decrease of the pH of the skin (with 14.32%) compared to the animals from the control group.
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