Diabetes mellitus is one of the most common metabolic disorders of multiple etiology. The multisystem effects of diabetes such as retinopathy, nephropathy, neuropathy and cardiovascular diseases have an important impinging on the working age individuals in our country. Diabetic Retinopathy (DR) is one of the leading causes of blindness in the world that increases the chance of losing vision to about 25 times higher compare to normal individuals. Diabetic Nephropathy (DN) is the major life-threatening complication which develops in approximately 20% to 40% of type 1 and less than 20% of type 2 diabetic patients. DN is the leading known cause of End stage renal disease (ESRD). AIM AND OBJECTIVE: A systematic cross-sectional study was conducted in Sarojini Devi eye hospital to assess the correlation between Diabetic Retinopathy and Diabetic Nephropathy in Type II Diabetes Mellitus patients. METHODS AND MATERIALS: A study was conducted on 108 Type II DM patients presenting to Sarojini Devi Eye hospital, Hyderabad and were assessed for Retinopathy and Nephropathy and Correlation between Retinopathy and Nephropathy was studied from December 2011 to December 2014. RESULTS: Out of 54 Diabetic Retinopathy patients, 28 (51.8%) patients had DN, 26 patients (48.2%) had no evidence of DN. Out of 54 Diabetic Nephropathy patients, 36(66.6%) had DR; 18(33.4%) had No evidence of DR. CONCLUSION: The results of our study suggest that Diabetic Nephropathy has a positive association with the presence of Diabetic Retinopathy in persons with Type II DM.