<p class="abstract"><strong>Background:</strong> Keloid is a common presentation in clinical practice. Symptoms due to keloid are mild, but disfigurement and functional impairment can be severe. It is difficult to treat. Intralesional, injection triamcinolone acetonide, has limited efficacy, causes adverse effects such as local dermal atrophy, telengiectasia and hypopigmentation. Injection verapamil is reported to have similar efficacy, but lesser side effects, and is cheaper. Aim was to study efficacy and adverse effects of intralesional verapamil in treatment of keloid.</p><p class="abstract"><strong>Methods:</strong> An open label study on 25 patients of keloid, either gender, age 11 to 55 years at a medical college hospital. Injection verapamil 2.5 mg/ml was administered intralesionally, at an interval of 3 weeks, for a total of 6 sittings, over a period of 18 weeks. Vancouver scar scale (VSS) was used to assess the improvement. The statistical analysis was done using SPSS version 21.0.<strong></strong></p><p class="abstract"><strong>Results:</strong> Median duration of keloids was 8 months. The mean VSS score before treatment was 7.68 which reduced to 4.28 after treatment. Mean percentage change in VSS score was 46.21%, very highly significant (p&lt;0.001). Physician’s assessment was ‘very good’ in 32.0% and 'excellent' in 8.0%. The complaint of post-procedure pain was present in almost all.</p><p class="abstract"><strong>Conclusions:</strong> Intralesional injection verapamil, gives very good to excellent improvement in 40% of patients of keloid. Post injection pain persists for more than 24 hours. Drug does not cause local dermal atrophy or hypopigmentation.</p>

<p class="abstract"><strong>Background:</strong> Uncontrolled use and abuse of topical steroids has led to increase in number of cases of superficial dermatophytosis of skin, hair and nail in pediatric age group as well. Our study aimed to analyse epidemiological and microbiological profile of steroid modified tinea (SMT) in pediatric age group.</p><p class="abstract"><strong>Methods:</strong> Clinically diagnosed tinea childhood patients with history of usage of topical steroids in children were included in our study. Detailed history was taken and clinical examination along with KOH mount and culture was done.<strong></strong></p><p class="abstract"><strong>Results:</strong> 112 patients were clinically diagnosed as tinea out of which 61cases gave the history of topical steroids and were included in our study. Most common age group was 12-18 years with female:male of ratio approximately 3:1 and disseminated and atypical form was the most common variety. KOH mount was positive in 73.2% cases and culture was positive in 69.6% cases. Most common species found out to be <em>Tinea mentagrophytes</em> followed by <em>Tinea rubrum</em>. Among non-dermatophyte group, <em>Candida</em> was the commonest.</p><p class="abstract"><strong>Conclusions:</strong> There is rise in incidence of dermatophytosis, especially steroid modified, atypical and disseminated.</p>

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<p class="abstract"><strong>Background:</strong> Rampant use and abuse of topical steroids has led to increase in number of cases of superficial dermatophytosis of skin, nail and hair. In most of the cases they are resistant to topical as well as oral antifungals even after prolong course of treatment. Our study aims to analyse epidemiological and microbiological profile of steroid modified tinea (SMT).</p><p class="abstract"><strong>Methods:</strong> Clinically diagnosed tinea patients with history of usage of topical steroids were included in our study. Detailed history was taken and clinical examination along with KOH mount and culture was done.<strong></strong></p><p class="abstract"><strong>Results:</strong> 980 patients were screened of which 550 patients with history of using topical steroids were included in our study. Most common age group was 20 to 29 years with male: female of ratio approximately 3:1 and disseminated form was the most common variety. KOH mount was positive in 76% cases and culture was positive in 72% cases. Most common species came out to be <em>T. Mentagrophytes</em> followed by <em>T. rubrum</em>. Among non-dermatophyte group, Candida was the commonest.</p><p class="abstract"><strong>Conclusions:</strong> There is<strong> </strong>rise in incidence of dermatophytosis, especially steroid modified one and cases of disseminated tinea are rising.</p>

<p class="abstract"><strong>Background:</strong> Cutaneous manifestations are common in elderly. The elderly population is composed of persons over 60 years of age and very few studies are available on the dermatologic diseases in this group. This study was done to study the clinical pattern and frequency of cutaneous manifestations in the elderly.</p><p class="abstract"><strong>Methods:</strong> A cross sectional observational study was conducted on 540 patients, aged 60 years and above, who attended the out-patient department and admitted as inpatients having cutaneous manifestations were included, in the department of dermatology Era’s Lucknow Medical College And Hospital, Lucknow.  A detailed history was taken regarding the onset and duration of cutaneous manifestations. Thorough dermatological examination was carried out on all study patients. Relevant investigations which included haemogram, biochemical tests and a skin biopsy were performed, wherever needed. Skin changes in all the patients were recorded and were classified into physiological and pathological changes. Data were entered in an Excel sheet and were analyzed using descriptive statistics.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 540 patients studied, 55.7% were males and 44.3% were females. Pruritus was the single most common complaint elicited (90.6%). Among the physiological changes, wrinkling was the commonest (80.9%). Among the pathological changes skin tumours, eczemas, infections were the common findings.</p><p class="abstract"><strong>Conclusions:</strong> The geriatric dermatoses are different in different populations, as there is significant number of geriatric population, the increased emphasis on geriatric medicine is   inevitable.  This    present study helps in providing greater understanding of pattern of geriatric dermatoses that aids in early diagnosis and management.</p>

<p class="abstract"><strong>Background:</strong> Cutaneous manifestations are common in neonates. Transient and pathological neonatal dermatoses should be differentiated to avoid unnecessary treatment and thus considering the variable nature and severity of neonatal skin lesions, it is important to be aware of the transient skin lesions in newborn and to differentiate these from other serious conditions which will avoid unnecessary therapy to the neonates and the parents can be assured of good prognosis of these skin manifestations. The present study has been carried out to study the clinical pattern of cutaneous lesion in neonatal period.</p><p class="abstract"><strong>Methods:</strong> A total of 255 neonates from Department of Dermatology in collaboration of Department of Pediatrics, Era’s Lucknow Medical College and Hospital were evaluated for cutaneous manifestations. A detailed assessment regarding history, clinical examination and investigations were recorded and analyzed.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 255 neonates, 138 (54.1%) were males and 117 (45.9%) were females. The sex ratio (M:F) was 1.18. The most common dermatoses were physiological desquamation (54.1%) and mongolian spots (37.6%) followed by milia (19.6%), miliaria (14%), epstein pearls (10.2%).</p><p class="abstract"><strong>Conclusions:</strong> The physiological and transient cutaneous lesions are common are in neonates. Physiological cutaneous manifestations were quite frequent apart from birthmarks/congenital cutaneous manifestations. An understanding of these manifestations helps in managing and deciding the appropriate manifestation.</p>

<p class="abstract"><strong>Background: </strong>Psoriasis relatively common, chronic, inflammatory and hyper-proliferative skin disease that affects 1.4% to 2.0 % of the population. Pateints with psoriasis have to face severe problems with stigmatization, discrimination and negative attitudes in general among the public, and often bear the brunt of public rejection.</p><p class="abstract"><strong>Methods: </strong>A cross-sectional observational study was carried out on psoriasis patients attending dermatology outpatient department of Era’s Lucknow medical college and hospital between November 2018 and November 2020. Patients with pustular psoriasis, mycosis fungoides, pityriasis rubra pilaris, and other severe medical conditions like heart failure, liver cirrhosis were excluded from the study.</p><p class="abstract"><strong>Results: </strong>Present study included 170 (aged 16 to 76 years; mean age 37.74±13.70 years; 62.4% males) clinically diagnosed patients of Psoriasis. P-score was observed with increase in Body Surface area, maximum for cases with BSA ≥25%. There was a strong positive significant linear correlation between stigmatization scores and disability scores (r=0.746; p&lt;0.001), thus indicating that with increase in p scores there was a significant increase in PDI scores and vice versa.</p><p class="abstract"><strong>Conclusions:</strong> Present study showed that feeling of stigmatization and disability was highly prevalent in psoriasis patients. It was seen that stigmatization and disability showed a strong correlation. The findings of study showed that there is need to create awareness regarding psoriasis as a non-communicable disease in order to increase the acceptance of psoriasis patients in society and to reduce their stigmatization.</p><p class="abstract"> </p>