Gliding arc discharge (GAD) has the properties of both thermal and nonthermal plasma conditions. GAD plasma in the atmospheric pressure with argon/nitrogen and its characteristics are described. Some experimental results about alternating current gliding arc plasma generator have been obtained. It seems that the current density strongly depends on the gas type, and increased with increasing discharge current and gas flow rate. In addition, the discharge current of GAD in nitrogen gas (N 2 ) is greater than one in argon gas (Ar) because of N 2 needs more breakdown voltage than Ar. The intensity of GAD increased with increasing the gas flow rate. The oscillograms of discharge current in each case of Ar and N 2 were obtained. The electron temperatures of Ar and N 2 plasma were calculated to be 22 800 and 8400 K, respectively. The characteristics of both Ar and N 2 gases in atmospheric pressure, such as current density, electron density with flow rates (5, 10, 20, and 40) standard cubic foot per hour, were investigated and all experimental results were classified. An experimental study was carried out through using of GAD device for medical treatment by exposing three human blood samples of leukemia to the nonthermal GAD plasma for different periods.Index Terms-AC gliding arc discharge (GAD) device, argon and nitrogen gases, diagnostic technique, discharge at the atmospheric pressure, gas flow rate, nonthermal plasma.
Scattered ionizing radiation emissions from a low-energy plasma focus (0.1 kJ Mather-type) device operating with different gases were studied. The plasma focus device was powered by a capacitor bank of 1 μF at 18 kV maximum charging voltage. The radiation emissions were investigated using time-integrated thermoluminescence TLD-500. These detectors were calibrated against standard X-ray machine as well as standard γ sources ( 60 Co and 137 Ca). Calibration of detectors showed linear relation over all the region of measurements. It was found that radiation levels would be minimum for different gases, when the gas pressure was between 0.5 and 0.8 Torr. Only helium deviated from this phenomenon as it gave maximum radiation level at 0.8 Torr pressure. It was also found that, for all the gases used, the radiation levels were maximum when the applied voltage was 15 keV.
This article presents a trial of the treatment of chronic-phase (CP) and accelerated-phase (AP) chronic myelogenous leukemia (CML) that is resistant or only partially responded to chemotherapy. Blood samples of 6 cases diagnosed with CML were studied and compared with a control group. The first 3 cases were AP CML resistant to imatinib and nilotinib. The other 3 partially responded to the chemotherapy and returned to CP CML. Triple blood cultures for each case were exposed to a cold, pulsed, atmospheric pressure plasma jet for different durations (40, 80, and 120 seconds). Hematological, cytogenetic, and biochemical investigations were done before and after plasma jet exposure. The results showed an increase in necrotic and apoptotic cell counts and a decrease in the number of characteristic nucleoplasmic bridges (multinucleated threadlike shape). Concentrations of transforming growth factor-β1 and arginase decreased in the CML blood samples after exposure to plasma jet.This type of nonthermal plasma can kill cancer cells and prevent the cells from dividing, especially for the 80-second duration.
Preliminary results of recent experiments performed within the Mather-type 112.5 J plasma focus device are presented. The ion beams from the focus device operated with deuterium filling at 1 mbar were registered using CR-39 solid state nuclear track detectors (SSNTD) and a Faraday cup detector for time-resolved measurements. The time-resolved neutron emission from the focus region measurements was detected with a photomultiplier tube (IP-28) optically coupled with a plastic scintillator NE 102.
Hepatitis C virus (HCV) is a positive-strand RNA virus that causes severe liver diseases, such as cirrhosis and hepatocellular carcinoma. In this study, we investigated viral inactivation by DC and pulsed gliding arc discharge devices. Virus inactivation efficiency of HCV in human blood cells is about 67% within 2 min of the plasma exposure, using a nonequilibrium DC gliding arc discharge device.
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