We review 22 neuropsychological studies of frontal lobe functions in children with attention deficit disorder with and without hyperactivity (ADD/+H, ADD/-H). Some measures presumed to assess frontal lobe dysfunctions were not reliably sensitive to the deficits occurring in either form of ADD. Tests of response inhibition more reliably distinguished ADD/+H from normal children. Where impairments were found on other tests between ADD and normal subjects, they were highly inconsistent across studies and seemed strongly related to age of the subjects and possibly to the version of the test employed. Other methodological differences across studies further contributed to the discrepant (LD) and conduct problems, with ADD may be an additional confounding factor in some, though not all, of these studies. In a separate reports. The co-morbidity of other disorders, such as learning disabilities (LD) and conduct problems, with ADD may be an additional confounding factor in some, though not all, of these studies. In a separate study, children with ADD/+H (n = 12) were then compared on frontal lobe tests to three other groups: ADD/-H (n = 12), LD but no ADD (n = 11), and normal children (n = 12) statistically covarying for differences in conduct problems across groups. Most measures did not distinguish among these groups. Both ADD groups made more omission errors on a Continuous Performance Test (CPT) than the normal group. All three clinical groups performed more poorly on the word and interference portions of the Stroop Test. Thus, while both types of ADD share some apparent similarities in deficits on a few frontal lobe tests in this study, the totality of existing findings suggests an additional problem with perceptual-motor speed and processing in the ADD/-H group.
A battery of tests presumed to assess various frontal lobe functions in children was evaluated for the accuracy of the tests in classifying children as having attention deficit hyperactivity disorder (ADHD). Two groups of children were tested: (1) 66 children, ages 6-11 years, with ADHD, and (2) a normal community control group of 64 children of the same age. Results indicated good positive predictive power (PPP) for seven of the tests (ranging from 80 to 90%), suggesting that abnormal scores on these tests may be indicative of the presence of ADHD. However, the rates of negative predictive power (NPP) even for these seven tests were modest (ranging from 50 to 66%). Sensitivity was also poor (ranging from 5 to 43%) as were the levels of false negatives (averaging 40%) creating fair-to-poor overall classification rates for all tests (49 to 70%). It is concluded that while these neuropsychological tests may have some value in clinical evaluations of children's psychological abilities, they may not be useful as the sole criteria for the diagnostic classification of children as ADHD.
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