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Lipophilic substituted zinc(II) phthalocyanines: 2, 3,9,10,16,17,23,Ndi methylaminoethylsulfanyl)]phthalocyaninatozinc(II) (S1) and tetrakis(N,N-dibutylaminoethoxy) phthalo cyaninatozinc(II) (3) were incorporated into soybean L-α-phosphatidylcholine (SPC) liposomes of 100 nm diameter. Liposomes were characterized by static light scattering (SLS), transmission electronic microscopy (TEM), and differential scanning calorimetry. The fluorescence quantum yield and singlet molecular oxygen production of 3 are Φ F = 0.15 and Φ ∆ = 0.24, respectively, whereas the same photophysical parameters for S1 are Φ F = 0.13 and Φ ∆ = 0.51. Higher values of Φ F and Φ ∆ are obtained in organic solvent for both dyes. Synthesis of compound 3 has also been reported.

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