A case of untreated primary hypoparathyroidism with psoriasis vulgaris is reported. On systemic prednisone therapy the patient developed generalized erythroderma, pustular psoriasis of the soles, candidiasis of the mouth, dermatogenic enteropathy and manifest tetany. Correction of the serum calcium improved the severe skin lesions, emphasizing that fluctuations in serum calcixim affect psoriasis.Hypoparathyroidism may be associated with dermatological diseases as diverse as impetigo herpetifor-
In 54 patients with lupus erythematosus – 6 with systemic, 19 with disseminated discoid, and 29 with localized discoid lupus erythematosus determination of the 3rd and 4th components of complement (C3 and C4) was performed in a prospective study. In relation to 42 healthy persons, the mean value of C3 proved significantly reduced in systemic lupus erythematosus, and the mean value of C4 was significantly reduced in systemic as well as in disseminated discoid lupus erythematosus. When C3 and C4 were related to disease activity, a depression of complement was found parallel to an increase in disease activity in all three forms of lupus erythematosus. Compared with other serological tests, C3 and C4 afforded the best serological evaluation of the disease activity. Alterations in the clinical condition in 8 of the patients with discoid lupus erythematosus were preceded by changes in C4. A single determination of C4 was diagnostic in 8% of the patients with discoid lupus erythematosus.
HLA-ABC antigens were determined in 89 patients with biopsy-confirmed lichen planus, and the HLA antigen frequencies were compared with those in 1967 controls. The younger patients were predominantly male, the older patients predominantly female. No significant association was found between HLA types and lichen planus in this study. A slightly greater incidence of HLA-A3 and B5 antigens was seen, but this increased frequency was not as pronounced as reported by others. When combined, available data on HLA and lichen planus indicate a slightly, but significantly, increased frequency of HLA-A3. None of the HLA antigens known to be associated with insulin-dependent diabetes are associated with lichen planus.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.