The dilated functional bowel segment was characterized by hyperplasic changes in the mucosa and stronger mechanical activity with overproduction of nNOS. Although early restoration of intestinal continuity is recommended, our observations on adaptive changes may partly explain intestinal motility disorders after early stoma closure, suggesting the need for a careful approach to a redo-laparotomy.
The measurement of enzyme activity in urine provides a sensitive assessment for renal tubular cell damage. The present study was undertaken to evaluate the clinical value of the determination of tubular brush-border-associated enzymes, alkaline phosphatase (AP), gamma-glutamyl transferase (GGT), leucine aminopeptidase (LAP), and dipeptidyl peptidase IV (DPP), of patients with normal graft function (NOR, n = 20), with acute tubular necrosis (ATN, n = ll), with an acute rejection episode (ARE, n = 17) after transplantation, and of healthy persons (n =20). The second urine of the morning was collected daily during the patients' stay in hospital. The enzyme activities were measured at 25 "C and were expressed as Uimmol creatinine. The enzymuria in NOR is higher than in healthy controls, but is still in the normal range. By 5 days after transplantation the initial increased excretion declines as the graft function
Summary. The aetiological significance of Acremonium kiliense is demonstrated for the first time in a human gastrointestinal infection. The mycotic oesophagitis with gastro‐oesophageal reflux is described. The situation was treated effectively with itraconazole and anti‐reflux surgery.
Zusammenfassung. Die ätiologische Beteiligung von Acremonium kiliense wird zum ersten Mai bei einer Gastrointestinaltrakt‐Infektion des Menschen nachgewiesen. Die Autoren beschreiben die pilz‐bedingte Ösophagitis mit gastro‐ösophagealem Reflux. Die Situation konnte mit Itraconazol und einem chirurgischen Eingriff wirksam saniert wer‐den.
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