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5. In the presence of 10 /M TCP, BK no longer produced significant effects on the AHPSloW In contrast, 10 #M TCP did not prevent PGI2 from blocking the AHPSlow.6. These results suggest that vagal afferents that exhibit AHPSlow also possess the B2 type of BK receptor. Activation of these BK receptors results in the production of PGI2, which in turn controls spike frequency adaptation by affecting the amplitude of the AHPSlow.

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