While dysthymia in AD is a brief emotional disorder, major depression is a longer-lasting mood change. Anosognosia is another prevalent disorder among AD patients, and increases with the progression of the illness.

Apathy, but not depression, is associated with significantly more severe frontal lobe related cognitive deficits in AD.

Major depression in patients with PD is associated with significant deficits on specific cognitive tasks. While some of these deficits may be explained by the presence of major depression, frontal lobe-related cognitive impairments may result from an interaction between neuropathologic factors in PD and the mechanism of major depression.

Objective-To examine neuropsychologi-

No abstract