Unilateral radiofrequency lesion versus electrostimulation of posteroventral pallidum: A prospective randomized comparison

Pallidotomy for Parkinson disease: a review of contemporary literature

“…According to AAN criteria, only one study provided Class I evidence; in this study a small number of patients with short follow-up periods were reviewed to compare radiofrequency pallidotomy and deep brain stimulation. 64 The two Class II studies also had small numbers of patients and nonrandomized control groups. 15,63 Available data from studies in which the UPDRS or Schwab and England ADL scale was used provided evidence of significant clinical improvement in patients after pallidotomy.…”

“…[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][22][23][24][54][55][56][57][58][59][60][61][62][63][64][65][66][67][68][69][71][72][73][74][75][76][77][78][79][80][81][82][83][84][85]…”

“…2,4,6,9,10,12,15,18,20,22,23,26,27,30,36,39,[42][43][44][45]48,52,54,56,[60][61][62][63][64]66,68,72,73,75,77,78,[81][82][83]86,88,89 The deaths were usually related to the occurrence of large intracerebral hemorrhages. Cerebral hemorrhages were the most significant complications, occurring in 26 cases (1.7%).…”

Bilateral pallidotomy for treatment of Parkinson's disease induced corticobulbar syndrome and psychic akinesia avoidable by globus pallidus lesion combined with contralateral stimulation

“…The surgical procedure has been described elsewhere4 13; briefly, it was microelectrode guided and both sides were operated on in a single intervention. At the site determined by electrophysiological parameters, a 75 degree 60 second lesion was performed either unilaterally or bilaterally.…”

“…Unilateral posteroventral GPi stimulation (PVS) may be as effective as unilateral PVP, with a similar frequency of side effects 13. Contemporaneous bilateral PVS has also been reported to be a safe and efficient technique,14 15 but results of a combination of both PVP and PVS have only been described in a single study 16…”