It is a well-established fact that the weight, size, histological appearance and secretory functions of certain accessory organs of reproduction, such as the seminal vesicle and the prostate, are strictly dependent on, and closely regulated by, the internal secretion of the testes; furthermore, that the typical retrogressive changes which occur in the accessory glands after removal of testes can be counteracted by injections of the testicular hormone, thus serving as 'indicator tests' for the male sex hormone
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