Personalized medicine refers to applying pharmacogenomics to clinical management of an individual which utilizes new molecular tools & technology to facilitate individualized health care based on person's unique characteristics enabling a higher level of personalization. Modifying genetic setup can prevent or cure a disease. Though the term personalized medicine Discovery of genes involved in drug metabolism & drug alternatives can prevent adverse drug interaction. This article highlights about personalized medicine & application of Pharmacogenomics in the field of Periodontology.
Smart phones are electronic gadget that is used for many purposes other than communication. Past few years data reveals increased smart phone buyers due to introduction of 4G network. The e-rays emitted from cell phone usually between 301MHz and 950 MHz depending upon the type of device, frequency and duration of use. Long duration of mobile use can lead to increase in temperature of the exposed areas and surrounding tissues. Mobile phone radiation increases production of singlet oxygen through NADPH oxidase, leading to oxidative stress that forms a major etiological factor for various diseases. Increased exposure to smart phone radiation could have ill effects on human body. Particularly, oral cavity & Perioral tissues are frequently exposed to mobile radiation compared to other parts of the body. This review highlights the possible mechanism between effects of cell phone radiations on oral tissues.
Process writing a review in systematic manner, by framing an Aim and Objective, having an inclusion criteria and exclusion criteria. Literature search is done both in the electronic and manually. Total number of journal which focus on the our aim is selected, the results and methodology is systematically evaluated META analysis is done and separate statistics is applied. Conclusion is given based on the various findings. Systematic review is the evidence based dentistry.
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