IFN-γ/CCR5 expression in iNKT cells and CCL5 expression in vessels of dermal papillae correlate with the development of psoriasiform hyperplasia and microabscess. We propose that these iNKT cells may become useful targets for development of novel therapeutic approaches to PV.
Ovarian-type epithelial tumors of the testes and paratestes are very rare. Mucinous subtypes of such tumors are extremely rare; only 25 cases have been reported to date. Ovarian-type epithelial tumors are histologically classified into cystadenomas, borderline tumors, and carcinomas. We herein report a case involving a 60-year-old man with a primary borderline mucinous tumor of the testis. He underwent orchiectomy and has developed no recurrence for 4 years. This is the 26th report of a mucinous tumor of the testis in the literature. We also herein review the literature and discuss the etiology, prognosis, and treatment of mucinous tumors of the testes.
Serous tubal intraepithelial carcinoma (STIC) has attracted attention as a precursor lesion of high‐grade serous carcinoma (HGSC) of the ovary. We report the rare case of a woman in whom adenocarcinoma cells were detected in cervical smears and demonstrated to be derived from STIC in the fimbria. The patient was a 48‐year‐old woman, in whom cervical smears contained adenocarcinoma cells, but cervical conization did not reveal adenocarcinoma. Because the post‐conization smears again demonstrated adenocarcinoma cells, hysterectomy with bilateral salpingectomy was performed 16 months after the first detection of adenocarcinoma cells in cervical smears. Histopathological examination demonstrated STIC in the fimbria of the left fallopian tube. Bilateral ovaries appeared grossly normal at that time, but oophorectomy, which was performed 3 months later, disclosed HGSC involving the surface of bilateral ovaries. Detection of carcinoma cells from STIC in cervical smears is of marked significance for the management of patients, and we should keep in mind the possibility that adenocarcinoma cells in cervical smears are derived from STIC. The postoperative outcome of patients with STIC is considered generally favorable, and the clinical course of the present patient, in whom HGSC involving the bilateral ovaries was found shortly after salpingectomy, is exceptional.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.