Four cases of Dowling Degos disease (DOD) in one family and five cases of Haber's syndrome (HS) in two families were compared. nOD and HS share many symptoms and findings in common; histopathological features of downgrowths of epithelial cells, papules of either brown or natural skin color, and various kinds of skin pigmentation. Some had pitted scars, cysts, pruritus, telangiectasia, red cheeks, xerosis, and photosensitivity. Another feature common to both conditions is the progressive course of the disease; patients and their children should be followed over their lifetimes. One case of DOD had basal cell epithelioma within the area of reticular pigmentation, but an 83year-old patient with DOD indicated that general health is not involved in DOD.One differentiating point for HS is that black warts in HS do not have the histologic features of DDQ.; they show only seborrheic keratosis. In HS, microscopic examinations should be made of as many varied lesions as possible.HS appears to be a subtype of ODD, characterized by red facies, seborrheic keratosis, and earlier onset than DOD. Both DDD and HS appear to be conditions with a different reactivity of the melanoeyte-keratinocyte system to external stimulation, rather than a disease of nevoid origin.
It is well known that in the course of antibiotic treatment there sometimes occur alterations in enteral bacterial populations and superinfections as a results of the disruption of the usual enteral bacterial flora.It is also recognized that the certain bacterial flora such as enterococci can provide the host animals with the resistance to some intestinal infections such as salmonellosis.The authors tried Entomol-San, an antibiotic resistant enterococcus (streptococcas faecalis BIO-4R) preparation on patients of bacillary dysentery, its suspects, and salmonellosis and its clinical effects were evaluated in this paper.Entomol-San was administrated in combination with antibiotics and its eradication effects on Shigella and Salmonellae were compared with the control (cases with antibiotic only). Recognizable differences were not observed between them. However, in the effects to the normalization of the stool appearances Entomol-San yielded better results than antibiotic alone. In the cases with Entomol-San and antibiotics, the mean requiring day for the normalization of stool appearances was 3.3 in 11 dysentery cases, 5.63 in 11 salmonellosis, and 3.47 in 15 cases of acute enteritis without known pathogens. These data appeared obviously superior to the results obtained by the 1971's study team in antibiotic therapy of intestinal infectious diseases.Further, the bacteriological investigations revealed that BIO-4R strains could often be recovered from the feces of the patients after Entomol-San administrations. In the mixed culture, the drug resistance of BIO-4R was not transferred into Escherichia coli K-12 strains,
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.