The emergence of a new coronaviral respiratory disease calls for repurposing existing drugs

Clinicians should be aware of the signs and symptoms of syphilis as well as current guidelines for the management and treatment of this disease.

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Objectives. In 1999, the University of Kentucky (UK) College of Pharmacy first reported the development of a STLC Program for pharmacy residents. The primary goal of this program was to provide a forum for participants to gain knowledge of contemporary health professions and pharmacy education issues, to develop experience in teaching/learning, and to document accomplishment in this area. Methods. The STLC program was designed as an elective experience that would provide residents with training in various teaching methodologies and offer a forum through which accomplishment in the area could be documented. The program consists of 3 main requirements: attendance at formal seminars, completion of a requisite amount of small group and didactic evaluated teaching, and submission of a teaching portfolio. Results. Since its inception the program has grown beyond UK and now involves 1 other onsite program and two-way teleconferencing to 2 other residency programs. Since 1999, over 50 residents have been awarded certificates. Summary. Feedback from residency candidates, residents, and employers has been overwhelmingly positive. Future plans involve increased multidisciplinary involvement and continued outreach to other offsite programs.

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Commonly referred to as "poppers," inhaled nitrites have a long history of abuse. Poppers are rapid-onset, short-acting potent vasodilators that produce a rush characterized by warm sensations and feelings of dizziness. Poppers sometimes are used to facilitate anal intercourse because of their actions on the anal sphincter. Epidemiologically, the frequent use of nitrites by men who have sex with men has led some experts to implicate these chemicals in the pathogenesis of Kaposi's sarcoma and acquired immunodeficiency syndrome. Controlled clinical trials to examine this potential correlation have not been conducted, and the use of nitrites simply may be a marker for other high-risk behaviors such as unprotected sex. Although regulated in the United States, many nitrite compounds and isomers are sold at various venues including bars, bookstores, and over the Internet. Adverse effects associated with these products vary from mild allergic reactions to life-threatening methemoglobinemia. The potential for drug-drug interactions and a propensity toward unsafe sex also exist. Clinicians should be familiar with the populations most likely to abuse these agents and with the clinical effects and management guidelines for acute ingestions.