No abstract

No abstract

No abstract

No abstract

A review of the literature on the in vivo action of dysentery-phage does not enable one to formulate any definite conclusions as to its value (Morton and Engley, 1945). There are about twice as many favorable as unfavorable reports. However, the use of dysentery-phage in man has been made under such poorly planned or executed experiments as to invalidate the results. The logical sequence of events should have been the testing of dysentery-phage in experimental animals, after the discovery of its action in vitro, before trying it on humans. To our knowledge this was not done. We wished to know whether dysentery-phage had any action in vivo and whether it would be reasonable to expect any prophylactic or therapeutic action in man. We feel that the results of animal experiments to be reported answer both questions in the affirmative.