Aim: It is important to find biomarkers that identify the graft quality in kidney transplantation. Results & methodology: The level of SLPI in the cold preservation solution was used as a marker to predict early kidney graft function after transplantation. Before transplantation, kidneys were washed and SLPI was measured in the discarded solution. A retrospective analysis showed that patients with delayed graft function or rejection episodes in post-trasplant, had higher SLPI concentrations in the perfusion solution than patients without delayed graft function or rejections. Furthermore, SLPI could discriminate between patients with better or worse estimated glomerular filtration rate among low-risk patients (kidney donor profile index <80). Discussion & conclusion: These results suggest that the SLPI concentration in the perfusion solutions could be a predictor of short-term organ function and a complement to the kidney donor profile index score.
Objective: To describe the characteristics of liver abscesses, bacteriology and evaluate the results of percutaneous drainage. Methods: Retrospective observational study, were included 23 patients with liver abscess, hospitalized and underwent percutaneous drainage, in the Hospital de Clinicas (University school hospital) FCM-UNA, from June 2014 to June 2016. Results: They were located in the right lobe 82.6%, cryptogenic were 26%, 21.7% biliary caused by bacteremia 17.4%, 13% diverticulitis, liver cyst infected 13%, gastric fistula 4.3 % and colon cancer 4.3%, the culture was positive in 69.56%, Klebsiella was isolated in 17.3%, it was found in 95.6% leukocytosis and elevated alkaline phosphatase in 69.56%. The result was satisfactory drainage in 82.6%, with the placement of a single catheter. The average length of stay was 19.3 days and mortality was 4.3%. Conclusion: Most abscesses were located in the right lobe and the most frequent cause was cryptogenic. The most frequently isolated germ was Klebsiella pneumoniae. Percutaneous drainage was successful in most patients and the mortality round was low. Percutaneous drainage is a simple and safe technique, which could now be considered the "gold standard" in the treatment of liver abscesses.
common bile duct (CBD) and no evidence of neoplasm in the bile duct, duodenum or pancreas. A laparoscopic cholecystectomy, CBD exploration and possible choledochoduodenostomy were decided on. Intra-operatively, choledochotomy was performed, multiple stones and mucoid material extracted from the supraduodenal bile duct and choledochoscopy showed a distal retroduodenal CBD with intraluminal papillary tumor projections and an inflamed common hepatic duct with no tumor. Frozen section biopsy showed invasive adenocarcinoma. The choledoctomy was closed and cholecystectomy done. Staging Magnetic Resonance Imaging (MRI) showed no evidence of metastasis or vascular invasion. Pancreatoduodenectomy was performed 3 days later. She was discharged on postoperative day 10 in good condition. Results: The distal CBD tumor measured 3 Â 1 Â 1.5 cm. Consisted of IPNB with pT1 N0 grade-1 well-differentiated invasive adenocarcinoma. Surgical margins were negative. Conclusion:We are reporting a case of invasive carcinoma in IPNB in a non-verbal patient. Pancreaticoduodenectomy after a preceding incidental intraoperative diagnosis was performed. A high index of suspicion on finding intraluminal papillary growths in the distal CBD was key to diagnosis.
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