Sixty-three dogs with newly diagnosed lymphoma underwent complete staging and received the same chemotherapy. Diffuse large B-cell lymphoma was the leading histotype (44.4%), followed by peripheral T-cell lymphoma (20.6%). Indolent lymphomas accounted for 30.2% of cases. Most dogs with aggressive B-cell lymphoma had stage IV disease. Dogs with indolent and aggressive T-cell lymphoma had more often stage V disease and were symptomatic. Liver and bone marrow were predominantly involved in B-cell and T-cell lymphoma, respectively. The clinical stage was significantly related to substage, sex and total lactic dehydrogenase (LDH) levels. Aggressive B-cell lymphomas were more likely to achieve remission. Median survival was 55 days for aggressive and indolent T-cell lymphoma, 200 and 256 days for indolent and aggressive B-cell lymphoma, respectively. The prognosis of advanced indolent lymphoma does not appear to be appreciably different from that of aggressive disease. Familiarity with the various histotypes is critical to make the correct diagnosis and drive therapy.
common bile duct (CBD) and no evidence of neoplasm in the bile duct, duodenum or pancreas. A laparoscopic cholecystectomy, CBD exploration and possible choledochoduodenostomy were decided on. Intra-operatively, choledochotomy was performed, multiple stones and mucoid material extracted from the supraduodenal bile duct and choledochoscopy showed a distal retroduodenal CBD with intraluminal papillary tumor projections and an inflamed common hepatic duct with no tumor. Frozen section biopsy showed invasive adenocarcinoma. The choledoctomy was closed and cholecystectomy done. Staging Magnetic Resonance Imaging (MRI) showed no evidence of metastasis or vascular invasion. Pancreatoduodenectomy was performed 3 days later. She was discharged on postoperative day 10 in good condition. Results: The distal CBD tumor measured 3 Â 1 Â 1.5 cm. Consisted of IPNB with pT1 N0 grade-1 well-differentiated invasive adenocarcinoma. Surgical margins were negative.
Conclusion:We are reporting a case of invasive carcinoma in IPNB in a non-verbal patient. Pancreaticoduodenectomy after a preceding incidental intraoperative diagnosis was performed. A high index of suspicion on finding intraluminal papillary growths in the distal CBD was key to diagnosis.
Biliary TBC is a rare entity, possibly underdiagnosed and is, therefore, a diagnostic and therapeutic challenge today, due to the increase in its incidence in the population. There are no pathognomonic characteristics of imaging diagnosis of biliary TBC; for this reason, it is obtained by histopathological study of the piece. We present the clinical case of a 29-year-old female patient who consults for progressive jaundice, choluria, and pruritus. As the only antecedent of hierarchy, she is the veterinary of large animals. The patient is studied with laboratory, ultrasound and magnetic resonance, with suspected bile duct tumors. Surgical behavior is decided with gallbladder and bile duct resection and biliodigestive anastomosis with pathological anatomy and PCR (C-reactive protein) that reports TBC of the bile duct.
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