Objective: In order to identify the available scientific production regarding photobiomodulation therapy in wound repair associated with diabetes mellitus. Methodology: This is an integrative review seeking primary studies conducted in the databases MEDLINE, LILACS, and SCOPUS, from 2015 to 2020. Results: It was analyzed 18 articles. The year that most published articles related to the theme was 2016 and 2018 with 28 % of articles each. Regarding the place of study 72 % of them were international and 28 % national. Regarding the analysis of the evidence levels of the articles, 94 % of the articles were in level 2 of evidence. As for the samples used in the studies, 50% of the studies used in vivo samples, 39 % clinical samples and 11 % were in vitro. 83 % used laser, 11 % used LED and 6 % used two (laser and LED). At about the power density used, it ranged from 1.08 mW / cm2 to 1920 mW/cm2. Energy density ranged from 0.2 J/cm2 to 6 J/cm2. The power ranged from 5 mW to 80000 mW. Application time ranged from 12 to 1066 seconds. The most commonly used wavelength was 660 nm. Conclusion: Studies rectify the efficacy of photobiomodulation therapy alone or in combination with other treatments, humans as well as animals or in vitro, in wound repair associated with diabetes mellitus.
This study aimed to evaluate the effect of LED photobiomodulation therapy associated or not with heterologous fibrin biopolymer to repair skin wounds in rats. Full-thickness skin wounds were induced on the back of 84 Wistar rats and they were randomly divided into 4 groups: control group (CG), LED group (LED), heterologous fibrin biopolymer group (HFB), and LED + heterologous fibrin biopolymer group (LED + HFB). The animals were euthanized at 7, 14, and 21 days after surgery. In the macroscopic findings, it was observed in the control group, mild local inflammation, evidenced between the 5th and 6th day after the injury, not manifested in the other groups. The analysis of the wound reduction index shown that the treated groups presented greater wound reduction in the three periods evaluated. The results of the degree of inflammation showed that the LED and LED + HFB groups showed a predominance of chronic inflammation, while the control group showed a predominance of diffuse acute inflammation. The quantity of type I collagen it was bigger after 7 days in the LED and LED + HFB groups, and at 14 and 21 days this type of collagen appears more intensely in the group that used only HFB. The traction force at 7 days of the experiment, the treated groups showed better performance, while at 14 and 21 days the group that used only the biopolymer obtained greater strength in the suture region. Results have indicated that treatments using HFB and LED, either isolated or associated, stimulated the wound repair process in rats. HFB promote collagen maturation.
Objetivo: Analisar a prevalência dos germes relacionados às pneumonias associadas à ventilação mecânica e seus perfis de sensibilidades. Métodos: estudo epidemiológico, descritivo com abordagem quantitativa. A amostra constou de 99 pacientes em uso de ventilação mecânica em duas unidades de terapia intensiva em um hospital público e de ensino do município de Teresina-Piauí. Os dados foram coletados por meio de um formulário nos meses de janeiro e fevereiro de 2009, processados estatisticamente e apresentados em forma de tabelas. Resultados: Os germes mais prevalentes foram: klebsiella spp (40,40%); Bacilo Gram-Negativo não fermentador (24,24%); Staphylococcus aureus e pseudomonas aeruginosa (17,17%). Evidenciou-se maior sensibilidade bacteriana ao imipenem (76,77%); meropenem (72,73%) e cefepime (58,59%). Conclusão: Terapêutica adequada e estratégias de prevenção reduzem as taxas de prevalência de pneumonia associada à ventilação mecânica e o surgimento de resistência microbiana.
Introdução: O presente estudo avaliou o perfil epidemiológico do SARS-CoV-2 no Estado do Maranhão, referente aos casos confirmados até junho de 2020. Delineamento: Trata-se de um estudo epidemiológico, descritivo, de casos e óbitos pela Covid-19 notificados no estado do Maranhão, no período de março a junho de 2020. Os dados foram analisados a partir dos boletins epidemiológicos de saúde do estado do Maranhão, juntamente com informações disponibilizadas pelas sedes regionais de saúde do estado. Os casos foram analisados por meio das variáveis: sexo (feminino e masculino), faixa etária (em anos), e presença ou não de comorbidades. Resultados: Foram confirmados 6.2711 casos de Covid-19. A região mais acometida foi a de São Luís com 12.095 confirmados, sendo os pacientes, em sua maioria, do sexo feminino (53%) e de idade entre 30 e 39 anos (19,85%). Os casos de pacientes do sexo masculino apresentaram maior taxa de óbitos (62%), prevalência de idade de mais de 70 anos (52,56%), comorbidades diversas (88%), destacando-se as doenças cardiovasculares e metabólicas. Implicações: A curva epidemiológica da doença é ascendente no estado, o que evidencia a necessidade de reforçar medidas de contenção e valorização dos recursos humanos.
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