and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden. OBJECTIVE To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic Index (SDI) quintiles from 2010 to 2019. EVIDENCE REVIEWThe GBD 2019 estimation methods were used to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life years (DALYs) in 2019 and over the past decade. Estimates are also provided by quintiles of the SDI, a composite measure of educational attainment, income per capita, and total fertility rate for those younger than 25 years. Estimates include 95% uncertainty intervals (UIs).FINDINGS In 2019, there were an estimated 23.6 million (95% UI, 22.2-24.9 million) new cancer cases (17.2 million when excluding nonmelanoma skin cancer) and 10.0 million (95% UI, 9.36-10.6 million) cancer deaths globally, with an estimated 250 million (235-264 million) DALYs due to cancer. Since 2010, these represented a 26.3% (95% UI, 20.3%-32.3%) increase in new cases, a 20.9% (95% UI, 14.2%-27.6%) increase in deaths, and a 16.0% (95% UI, 9.3%-22.8%) increase in DALYs. Among 22 groups of diseases and injuries in the GBD 2019 study, cancer was second only to cardiovascular diseases for the number of deaths, years of life lost, and DALYs globally in 2019. Cancer burden differed across SDI quintiles. The proportion of years lived with disability that contributed to DALYs increased with SDI, ranging from 1.4% (1.1%-1.8%) in the low SDI quintile to 5.7% (4.2%-7.1%) in the high SDI quintile. While the high SDI quintile had the highest number of new cases in 2019, the middle SDI quintile had the highest number of cancer deaths and DALYs. From 2010 to 2019, the largest percentage increase in the numbers of cases and deaths occurred in the low and low-middle SDI quintiles. CONCLUSIONS AND RELEVANCEThe results of this systematic analysis suggest that the global burden of cancer is substantial and growing, with burden differing by SDI. These results provide comprehensive and comparable estimates that can potentially inform efforts toward equitable cancer control around the world.

most elderly did not show significant changes in their sociodemographic, behavioral and health characteristics; the need to rethink more effective actions to improve the elderly health stands out.

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BackgroundCurrently, diabetes mellitus (DM) and systemic arterial hypertension (SAH) are among the top five global risks for mortality. Among the modifiable factors, careful dietary practice is one of the essential elements for the control of NCDs, since these diseases are often the result of unhealthy lifestyles. Thus, this study aimed to assess the frequency of dietary practices among adult males and females with DM and/or SAH, and compare whether or not they are more frequent than in healthy adults, through a population-based study conducted in the city of Florianópolis, southern Brazil.MethodsCross-sectional population-based study, using as exposure self-reported DM and/or SAH status. Dietary practices were assessed using a semiquantitative food consumption questionnaire. The following were considered as adequate: regular intake (≥ 6 times/week) of fruit and vegetables, daily intake of fruit (≥ 3 times/day) and vegetables (≥ 2 times/day), intake lower than 2 times/week of meat fat, fried foods, and soda. Bivariate and adjusted analysis for sociodemographic variables were conducted using Poisson regression, stratified by gender.Location: Florianópolis, southern Brazil, 2009.Subjects: Representative sample of 20 to 59 year-old adults (n=1720).ResultsA total of 16.6% participants were diagnosed with DM and/or SAH. The most frequently consumed unhealthy foods were fried food (51.0%, 95% CI: 48.8–53.5) and soda (57.9% 95%CI: 55.5–60.2). Of healthy foods, fruit was the less consumed on a daily basis (11.1% 95%CI 9.6-12.5). In general, women showed better dietary practices than men. In adjusted analysis none of dietary practices was more frequent among diabetic and/or hypertensive adults compared with healthy individuals, regardless of gender. No differences were found between healthy and unhealthy adults, when the number of dietary practices was assessed.ConclusionsThe frequency of dietary practices was low and did not differ between individuals with or without DM and/or SAH. It is fundamental to reinforce the need of healthy dietary practices as one of the essential elements for the control of chronic diseases and their complications.

ObjectiveThe aim of this study was to examine the associations between sedentary behavior and different intensities of physical activity with cardiometabolic risk, and to analyze the simultaneous effect of excess sedentary behavior and recommended levels of physical activity on cardiometabolic risk markers in older adults.MethodsWe conducted a population-based cross-sectional study on a sample of older adults (60+) living in Florianopolis, Brazil. The objectively measured predictors were sedentary time, light physical activity and moderate to vigorous physical activity, and the outcomes were markers of cardiometabolic risk. Data were considered valid when the participant had used the accelerometer for at least four days per week.ResultsThe sample included 425 older adults (59.8% women), with a mean age of 73.9 years (95%CI: 73.5–74.4). Sedentary behavior was associated with lower systolic blood pressure levels (β = -0.03; 95%CI: -0.05; -0.01) and lower HDL cholesterol (β = -0.02; 95%CI: -0.02; -0.01). Light physical activity was not associated with any cardiovascular risk markers after adjustment. Each minute spent in moderate to vigorous physical activity was associated with lower waist circumference (β = -0.15; 95%CI: -0.24; -0.05), systolic blood pressure (β = -0.18; 95%CI: -0.32; -0.04) and plasma glucose (β = -0.18; 95%CI: -0.33;-0.02), and with higher HDL cholesterol (β = 0.10; 95%CI: 0.01; 0.18). Moreover, physically inactive and sedentary individuals had a greater mean waist circumference and lower HDL cholesterol than physically active and non-sedentary subjects.ConclusionThe results suggest that moderate to vigorous physical activity have a positive impact on cardiometabolic risk markers in older adults. Light physical activity does not appear to have a beneficial effect on the cardiometabolic markers, and despite the benefits provided by the different intensities of physical activity, the simultaneous presence of sedentary behavior and low physical activity level was associated with poor cardiometabolic risk markers.

RESUMO: Objetivo: Investigar a prevalência da simultaneidade de fatores de risco cardiovasculares e sua associação com características sociodemográficas em idosos no sul do Brasil. Metodologia: Estudo transversal com 1.553 idosos participantes do Estudo Epidemiológico das Condições de Saúde dos Idosos de Florianópolis (EpiFloripa Idoso), Santa Catarina. Os fatores de risco foram: insuficiência no consumo de frutas, legumes e vegetais (FLV), insuficiência de atividade física no lazer, consumo abusivo de álcool e tabagismo. Construiu-se a variável desfecho através da combinação de todos os fatores, categorizada em nenhum, um, dois, três e quatro fatores de risco. Foram realizadas análises bivariadas e multivariadas empregando-se a regressão de Poisson. Resultados: Constatou-se que 57,6% dos idosos convivem com a simultaneidade de fatores de risco para doenças cardiovasculares. A maior prevalência observada tanto nas mulheres quanto nos homens foi da insuficiência de atividade física com a insuficiência no consumo de FLV, sendo de 46,4 e 28,1%, respectivamente. A prevalência observada dos quatro fatores simultâneos foi maior entre os homens (2,5%) em comparação às mulheres (0,3%). O sexo masculino apresentou 11,0% mais probabilidade de acumular fatores de risco comparado ao sexo feminino. E cada ano a mais de escolaridade representa 4,0% a menos de probabilidade de acumular fatores de risco cardiovasculares. Conclusões: As diferenças entre a simultaneidade de fatores de risco e aspectos sociodemográficos devem ser consideradas na abordagem do idoso tanto em nível individual quanto na construção de políticas públicas.

Resumo: O objetivo do estudo foi investigar a associação entre o consumo alimentar inadequado de micronutrientes e indicadores de obesidade geral e abdominal. Análise transversal, da segunda onda do estudo longitudinal EpiFloripa Adultos, incluindo 1.222 indivíduos de 22-63 anos, residentes em Florianópolis, Santa Catarina, Sul do Brasil. Os dados de consumo alimentar foram obtidos mediante aplicação de dois recordatórios de 24 horas, sendo o consumo habitual e as prevalências de inadequação no consumo de cálcio, ferro, zinco, e das vitaminas A, C, D e E estimadas conforme as recomendações do Instituto de Medicina e do Conselho Nacional de Pesquisa dos Estados Unidos. O estado nutricional de obesidade geral foi determinado considerando-se valores do índice de massa corporal (IMC), e a obesidade abdominal, considerando-se valores da circunferência da cintura (CC). Para a maioria dos micronutrientes investigados (cálcio, vitaminas A, C, D e E), as médias de consumo mostraram-se aquém dos valores recomendados, com prevalências elevadas de inadequação para toda a amostra. Somente a inadequação no consumo de vitamina C foi maior entre indivíduos obesos (geral ou abdominal). Além disso, associação inversa foi observada entre o menor consumo de cálcio e ferro com valores maiores do IMC e da CC, e entre o menor consumo das vitaminas A e D com valores maiores da CC (β = -0,92cm; IC95%: -1,76; -0,08 e β = -0,69cm; IC95%: -1,32; -0,06, respectivamente), principalmente entre adultos jovens. Foi possível identificar a existência de associação inversa entre o consumo alimentar inadequado de micronutrientes e o estado nutricional de obesidade geral e abdominal também em uma amostra de adultos residentes no Sul do Brasil.

BackgroundBrazil is among the 10 countries with the highest prevalence of overweight in the world. The aim was to analyse the changes in the dispersion of body mass index (BMI) in the Brazilian population from the 1970s to 2013 in specific population groups.MethodsData were extracted from five national household surveys between 1974–1975 and 2013, including adults aged 20 to 64. We calculated SD, median, fifth and 95th percentiles of BMI for each sociodemographic category (sex, age, schooling) and survey year in order to explore whether changes in mean BMI are followed by changes in dispersion.ResultsDuring the period the mean BMI ranged from 22.7 kg/m2 to 26.6 kg/m2, with a much higher variation in the 95th percentile (+6.1 kg/m2) when compared with the fifth percentile (+1.8 kg/m2). The within-group differences increased over time. The SD increased in all categories analysed and was higher among women, lower schooling groups and the oldest group. An increase of 1.0 kg/m2 in the BMI mean was associated with an increase of 0.32 kg/m2 in the SD, 0.45 kg/m2 in the fifth percentile and 1.50 kg/m2 in the 95th percentile of BMI.ConclusionsPopulation changes occurred in BMI are more complex than the simple increase of its average. Concomitant to the increase in BMI, there was an increase in the within-group differences, showing that growing inequalities are not driven solely by sociodemographic factors.