Estriol vaginal gel (0.005%) administration significantly improved the vaginal health of natural postmenopausal women before and after vaginal surgery. Both sexual health and QoL also significantly improved after surgery.

Estriol vaginal gel (0.005%) therapy significantly improves the trophism of the vaginal mucosa and the sexual health and QoL of naturally postmenopausal women. These results confirm that low doses of vaginal estrogen must be considered as the first choice for the initial treatment of postmenopausal genitourinary symptoms.

Spindle cell lipoma (SCL) is a rare benign tumor which occurs most commonly in the posterior neck, shoulder and back. We report a rare case of SCL arising in peri-parotid soft tissues in a 66 year-old man. This is an unusual site for such a relatively rare lesion. The histological examination of the lesion showed the typical morphological features of SCL. Only four cases of SCL of the parotid region have been reported to date. Our case emphasizes the possibility that SCL may occur in the peri-parotid soft tissue and awareness of this possibility is crucial for pathologists to avoid confusion with others primary tumors of the parotid gland in which mature adipose tissue may be a metaplastic tumor component.

IntroductionGallbladder cancer commonly spreads by direct extension to the liver and adjacent organs of the gastrointestinal tract. Ovarian metastases by biliary origin, though known, are a very uncommon finding.Presentation of caseWe report a rare metastatic localization by gallbladder cancer, Krukenberg tumor mimicking a primitive ovarian cancer. A comprehensive critical review was performed and suggested strategies were analyzed.DiscussionThe prognosis of ovarian metastastes by biliary origin is very poor with an overall survival estimated at around 6 months. The variable clinical presentation, radiology and serum markers make the appropriate histological diagnosis mandatory.ConclusionThe presence of Krukenberg tumor should be considered in the work-up of gallbladder cancer.