Demographic and health information, including influenza-like symptoms, sick leave and postvaccination adverse events were collected via questionnaires. Cost-benefit analyses were performed from the employer's perspective. Results: A total of 1,022 employees took part in the study, with 504 choosing to be vaccinated against influenza, and 518 remaining unvaccinated. The rate of influenza-like illness (ILI) was lower among vaccinated (8.13%) than non-vaccinated subjects (30.31%). Fever and respiratory symptoms were associated with all ILI cases. ILI-related sick leave was taken by 58.54% of vaccinated employees with ILI and 71.34% of nonvaccinated employees with ILI. Vaccination was financially beneficial, with the employer saving up to US$ 53.00 per vaccinated employee when labour costs only were considered. Savings rose to up to US$ 899.70 when the operating income of each employee was also considered. Workplace vaccination of healthy adults against influenza had a clear impact on ILI rates, absenteeism and reduced productivity in this Malaysian company. The health benefits translated into financial benefits for the employer, with cost savings significantly outweighing the costs of the vaccination programme. (J Occup Health 2006; 48: 1-10)

Among the studied volunteers, ILI has significant impact on work productivity in terms of indirect costs. Implementing an influenza vaccination program would reduce the burden of ILI and save substantial amounts of money for the company.

Routine childhood vaccination against hepatitis A showed both health benefits and robust economic benefits in this analysis, supporting the recent decision of the Argentine government to implement such a program.

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Objective. To evaluate the healthcare and economic impact of routine hepatitis A vaccination of toddlers in Chile. Methods. We used a dynamic model of hepatitis