We emphasize the relatively favourable visual prognosis in patients suffering from inherited retinal dystrophies complicated with choroidal neovascularization. Therapeutic approaches other than laser treatment could be attempted in these patients.

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We report the clinical history of 2 patients affected with reticular dystrophy of the retinal pigment epithelium and central choroidal neovascularization. With time, spontaneous reduction of the subretinal fluid associated with consequent improvement of the visual acuity has been noted in our first case. The second patient showed a stable fibrotic subfoveal choroidal neovascularization. Conventional fluorescein angiography and indocyanine green videoangiography findings are illustrated. The differential diagnosis between other reticular pigmented lesions often associated with choroidal neovascularization is discussed.

The diagnosis of keratoconus is based on slip-lamp and keratometric findings, and its classification includes 4 different stages. In this study, we compare the ultrasound biomicroscopy (UBM) findings and the keratoconus index (KI) determined using UBM with the severity of the disease. By means of UBM (Humphrey Instruments system model 840) using a 50-MHz probe, we studied 49 eyes affected with different forms of keratoconus. Using a method previously described, we calculated the KI and compared these data with the findings obtained using videokeratography. The mean thickness at the corneal apex in keratoconic eyes was 0.369 mm, while the mean peripheral corneal thickness was 0.568 mm. The mean KI was 1.449 in keratoconic eyes. The KI increased according to the severity of the disease. The mean central keratometry power was 56.95, while the mean amount of steepening of the inferior cornea compared with that of the superior cornea was 8.16. UBM can be considered a useful tool in the study of keratoconus. Using high-frequency ultrasound, it is also possible to obtain reliable measurements of corneal thickness related to the severity of the disease determined by videokeratography.