To investigate the effect of balneotherapy on body mass index, adipokine levels, sleep disturbances, and quality of life in women with morbid obesity. Fifty-four women with morbid obesity were included in the study. The body mass indexes (BMI) and waist/ hip ratios (WHR) of the women were calculated. Subcutaneous fat thickness was measured using a *skinfold meter, and the percentage of adipose tissue was calculated. The *Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality, and the Nottingham Health Profile (NHP) was used to assess quality of life. In addition to routine biochemical tests, leptin, adipokine, visfatin from blood, and cortisol from saliva samples were studied. Participants were given 15 sessions of balneotherapy for 20 min each. After treatment, the laboratory and clinical parameters of the participants were *reevaluated. There was no statistically significant difference of BMI, WHR, and percentage of adipose tissue between before and after treatment measurements (p ˃ 0.05).There was a statistically significant improvement in PSQI and NSP scores (p ˂ 0.001). The levels of blood glucose, leptin, and visfatin were significantly decreased, and adiponectin was significantly increased after treatment (p = 0.047, p ˂ 0.001, p ˂ 0.001, and p ˂ 0.001, respectively).There was no statistically significant changes in salivary cortisol levels (p = 0.848). Patients with diabetes showed a statistically significant decrease in glucose levels after treatment (p = 0.017).There was a statistically significant decrease in low-density lipoprotein cholesterol levels in patients with dyslipidemia compared with pretreatment (p = 0.018). Balneotherapy improves sleep and quality of life of women with morbid obesity. After balneotherapy, glucose, leptin, adiponectin, and visfatin levels may change positively.

Objective: To determine whether ocular Demodex colonization results in differences in Schirmer test scores and Ocular Surface Disease Index (OSDI) questionnaire values in individuals with dry eye disease (DED) diagnosed for the first time. Method: Eighty-eight adults aged 40 to 68 years who were admitted to Ophthalmology outpatient clinic for routine ophthalmological examination or presbyopia examination and diagnosed with DED for the first time and who do not have any chronic disease were included in the study. All the patients were asked to complete the OSDI, which is widely used for assessing dry eye symptom severity and vision-related functioning. The Schirmer test was performed, and then two eyelashes were taken from the inferior eyelids of each eyes. After saline (0.09% NaCl) was added to the sample, it was quickly taken to the microbiology laboratory, which is located next to the Ophthalmology policlinic. The sample was evaluated by a parasitologist experienced in Demodex. Results: One hundred sixty-eight eyes of 84 patients were included in the study. Average Schirmer test score was 2.1±0.5, the OSDI questionnaire score was 61.82±10.95, and the mean age was 55.36±8.74 years in patients who had Demodex colonization (n=30), whereas the average Schirmer test score was 6.6±0.9 score, OSDI questionnaire score was 40.96±12.73, and the mean age was 49.12±6.87 years in patients without Demodex colonization (n=58). It has been observed that dry eye patients with Demodex colonization had a higher mean age (P: 0.001), higher mean OSDI score (P: 0.001), and lower average Schirmer test score (P: 0.001) compared with those without Demodex. The significant relationship between lower Schirmer test score and higher OSDI rates and occurrence of Demodex infestation continued after adjusting for mean age values (P=0.012; P=0.035). Conclusion: It was determined that the presence of ocular Demodex colonization was associated with the average Schirmer test scores, OSDI scores, and age values in patients with newly diagnosed DED. Demodex quantity was found increased in older aged patients, but the significant relationship between lower Schirmer test score and higher OSDI rates and Demodex infestation persisted even after controlling the mean age values. Supporting these findings with large-numbered and randomized-controlled studies will help in clarifying the association of the Demodex infestation with etiopathogenesis of dry eye.

This study assesses the interior air quality and infective factors in a hospital in Turkey to provide data about air quality to protect hospital workers. This study measured indoor air quality in eight different locations in a hospital, including particulate matter (PM2.5 and PM1), carbon dioxide, carbon monoxide, temperature, humidity and microbiological matter. The highest PM2.5 and PM1 concentrations were in emergency service, and the highest CO2 was measured in the paediatric clinic. The poor interior air quality results are the most important cross-sectional data. For all participants, the prevalence of eye, upper respiratory tract, lower respiratory tract, skin and non-specific sick building syndrome symptoms were 23.0%, 40.7%, 22.5%, 36.3% and 63.7%, respectively. When sick building syndrome symptoms and environmental factors were investigated, skin symptoms increased 1.82 times in areas with stagnant air flow (p = 0.046; OR = 1.823; 95% CI: 1.010–3.290). Non-specific symptoms increased 2.17 times in locations with dry indoor air (p = 0.039; OR = 2.176; 95% CI: 1.041–4.549). Hospital workers are exposed to conditions that may increase the risk of a variety of sick building syndrome symptoms. Although the air quality measurements were not above the recommended limits in the hospital, long-term exposures should be considered for those experiencing sick building syndrome-related symptoms.

Entomopathogenic fungi (EPFs) play an important role for regulating insect pest populations, as they exist in many different ecosystems. Within these fungi, Beauveria and Metarhizium spp. genera include species that are the most commercially important. The aim of this study was to determine the diversity and distribution of Beauveria and Metarhizium spp. in walnut fields of Kırşehir, Turkey, and to evaluate their pathogenicity against Cydia pomonella (L.) (Lepidoptera: Tortricidae). To perform this, 90 soil samples were collected from walnut fields where Beauveria and Metarhizium spp. were isolated from these soils, using selective media. The isolated 40 fungi were characterized based on their morphological and molecular characteristics including Bloc and β-tubulin gene sequences. Also, eight selected fungi were tested against C. pomonella larvae under laboratory conditions. The fungal isolates were identified as Beauveria pseudobassiana (15), B. bassiana (12), Metarhizium robertsii (11), and M. brunneum (13). M. brunneum ELA-38 caused 83% mortality within 2 weeks after application of 1 × 10 8 conidia/ml. Consequently, Beauveria and Metarhizium spp. are the common component of the soils collected from walnut fields and some of fungi obtained from this work might be beneficial in the future biological control programs of C. pomonella.

No abstract

No abstract

Enterobacter cancerogenus (formerly known as CDC Enteric Group 19; synonym with Enterobacter taylorae) has rarely been associated with human infections, and little is known regarding the epidemiology and clinical significance of this organism. We describe a community-acquired pneumonia case in a 44-year-old female due to E. cancerogenus. Identification and antimicrobial susceptibility of the microorganism was performed by the automatized VITEK 2 Compact system (bioMerieux, France). The clinical case suggests that E. cancerogenus is a potentially pathogenic microorganism in determined circumstances; underlying diseases such as bronchial asthma, empiric antibiotic treatment, wounds, diagnostic, or therapeutic instruments.

No abstract