Based on the findings of this study, the chlorhexidine chip reduced GCF PGE2 levels and had positive effects on clinical parameters and subgingival flora when used as adjunctive therapy to SRP in patients with chronic periodontitis.

Purpose: Ganoderma lucidum, a kind of mushroom used for its antioxidant, anti-inflammatory, and immunomodulatory activities, was investigated in the present study for its possible healing effect on calvarial defects with bone grafts.Methods:Wistar male rats (n = 30) were divided into 3 groups: 1) the control (defect) group (n = 10), 2) defect and graft group (n = 10), and 3) defect, graft, and G. lucidum treated group (n = 10). The G. lucidum was administered to the rats at 20 mL/kg per day via gastric lavage.Results:In the defect and graft group, osteonectin positive expression was observed in osteoblast and osteocyte cells at the periphery of the small bone trabeculae within the graft area. In the defect, graft, and G. lucidum treated group, osteonectin expression was positive in the osteoblast and osteocyte cells and positive osteonectin expression in new bone trabeculae. The expression of matrix metalloproteinase-9 (MMP-9) was positive in the inflammatory cells, fibroblast cells, and degenerated collagen fibril areas within the defect area.Conclusion:This study shows that, with its antioxidant and anti-inflammatory properties, G. Lucidum is an important factor in the treatment of calvarial bone defects.

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Excessive gingival display can be managed by variety of treatment modalities, depending on specific diagnosis. This case report demonstrates the successful management of excessive gingival display with a lip-repositioning and gingivectomy. A female patient aged 26 years reported with a chief complaint of gummy smile and was treated with this technique performed under local anesthesia with the main objective to reduce gummy smile by limiting the retraction of elevator muscles (e.g., zygomaticus minor, levator anguli, orbicularis oris, and levator labii superioris). The technique is fulfilled by removing a strip of mucosa from maxillary vestibule and creating a partial thickness flap between mucogingival junction and upperlip musculature, and suturing the lip mucosa with mucogingival junction, resulting in a narrow vestibule and restricted muscle pull, thereby reducing gingival display.

Background: The present study has been designed to compare the effect of root surface biomodification with EDTA for the treatment of buccal gingival recession with free gingival graft. Materials and methods: This randomized controlled parallel clinical trial, 34 patients of 40 existing tooth Miller Class I and Class II gingival recession were treated with free gingival graft (FGG). Forty teeth with recession were assigned randomly to receive the free gingival graft with or without the application of an EDTA gel. Pre-treatment (Day 0) and post-treatment 3. and 6. months gingival recession height(GRH), gingival recession width(GRW), probing depth (PD), clinical attachment level(CAL) and width of keratinized tissue WKT were measured. Results: In FGG+EDTA group statistically significant changes from baseline were found GRH decreased from 4.7±1.5 mm to 1.3±1.2 and WKT increased from 0.9 ± 0.9 mm to 5.5±1.8 mm. Also in FGG group, GRH decreased from 4.6±1.3 mm to 1.3±1.2 mm and WKT increased from 0.9 ± 0.7 mm to 5.4±1.5 mm. For FGG and FGG+EDTA, the average root coverage 74.14% and 69.26% was found. Conclusion: In the light of these data obtained with the root surface biomodification agent EDTA have no beneficial effect for root coverage. In the light of these data obtained with the root surface biomodification agent EDTA have no beneficial effect for root coverage. Keywords: Gingival recession, free gingival graft, EDTA, root coverage