ment for heart disease [1][2][3], type 2 diabetes mellitus [4,5], obesity related metabolic syndrome [6][7][8], both ischemic and hemorrhagic stroke [9][10][11][12], and many forms of cancer [13][14][15]. These benefits extend beyond physical wellness and into one's mental wellbeing. PA has been shown to be a viable option to help prevent the incidence and effectively manage disorders such as clinical depression, stress, and anxiety [16][17][18].Costs to treat diseases associated with a lack of regular physical activity have a distinctly negative impact on the American health care system. According to the Centers for Disease Control and Prevention the total costs of treating all cardiovascular disease in 2015 alone was over $650 billion dollars and is estimated to exceed $1 trillion by 2030 [19]. The American Diabetes Association estimates the annual healthcare cost of type 2 diabetes mellitus in 2012 at $245 billion, an increase of 41% from estimates five years prior in 2007 [20]. National expenditures for cancer in 2010 were estimated at just under $125 billion, a figure estimated to increase to over $157 billion by 2020 [21]. In total, it is evident that a few mostly preventable diseases account for a large and growing proportion of American healthcare costs.In addition to the financial burden due to insufficient physical activity, increased morbidity and mortality must also be considered. Heart disease alone accounts for nearly one-fourth of annual deaths in the United States (US) while cancer accounts for just over
Objective: The aim of this study was reviewed the scientific evidence of the relationship that could exist between the use of Platelet Rich Plasma (PRP) after the reconstruction of the Anterior Cruciate Ligament (ACL). Design: We performed a systematic using the following key words: platelet rich plasma AND anterior cruciate ligament. Abstracts were screened by a single reviewer. For those studies meeting the eligibility criteria, full-text articles were obtained. Results: From 127 studies found only 5 articles were included in this systematic review. We found the presence of inflammatory diseases, DM, advanced osteoarthrosis (grade III-IV), previous knee surgeries, malignant diseases, contrast allergy, renal disease and thrombocytopenia. Conclusion: The use of the platelet rich plasma after the ACL reconstruction with patellar tendon, demonstrates a better autograft recovery in terms of vascularization, bone remodeling and edema decreasing, achieving an earlier autograft homogenization.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.