SUMMARY OBJECTIVE To present scientific evidence based on a systematic literature review (PRISMA) evaluating the association of Kawasaki Disease (DK) and COVID-19 in children. METHODS For the selection of studies, a combination based on the Medical Subject Heading Terms (MeSH) was used. The Medline (Pubmed), LILACS, SciELO, COCHRANE, and BIREME databases were used. The search period for the articles comprised the last 10 years (2010 to 2020). RESULTS 840 articles with potential for inclusion were retrieved, one of which met the inclusion criteria and the guiding question that consisted of evaluating the association of Kawasaki disease and COVID-19 in children. CONCLUSION A significant increase in the incidence of Kawasaki-type diseases after the onset of the epidemic has been reported, suggesting an association between the COVID-19 epidemic and the high incidence of a severe form of KD. However, further studies are needed to conduct an investigation of the association between these two diseases.

OBJECTIVE: To present scientific evidence based on a systematic review of the literature (PRISMA) to systematize information on smell and taste alterations in patients diagnosed with COVID-19. METHODS: The studies were selected through combinations based on the Medical Subject Headings (MeSH). The MEDLINE (PubMed), LILACS, SciELO, and BIREME databases were used. The search encompassed articles published from January 2010 to May 2020, with no restriction of language or localization. RESULTS: A total of 665 retrieved articles had the potential for inclusion. Of these, two answered the research question, which was to verify the smell and taste alterations in patients diagnosed with COVID-19. CONCLUSION: The results found in this review demonstrated that there likely is an association between self-reported smell and taste dysfunctions and COVID-19 infection in such patients.

No abstract

No abstract

Introdução: Dentre as doenças crônicas não transmissíveis (DCNT) mais prevalentes, destacam-se o Diabetes Mellitus (DM) e a Hipertensão Arterial Sistêmica (HAS). Estas DCNT se relacionam ao estilo de vida, idade e gênero, e podem estar associadas a alterações audiológicas. Objetivo: Evidenciar os estudos já existentes na literatura a respeito da DM e a HAS e a sua relação com a perda auditiva. Estratégia de pesquisa: As buscas por artigos científicos ocorreram nas bases de dados eletrônicos Medline (Pubmed), LILACS e SciELO. Critério de seleção: Foram incluídos estudos sobre a relação da perda auditiva com a DM e HAS publicados nos últimos cinco anos, e, excluídas revisões de literatura, revisões sistemáticas e meta-análises. Resultados: Foram selecionados nove estudos evidenciando que a DM e/ou a HAS podem ser possíveis fatores de risco para o desenvolvimento da perda auditiva; para isso foram realizadas avaliações e comparações de grupos de pessoas com e sem tais fatores de risco. Outras comorbidades podem ser determinantes para a perda auditiva. Após a análise, verificou-se que existe uma relação entre a HAS, DM e a perda auditiva, principalmente em altas frequências. Não foi observada nenhuma diferença entre as orelhas. Conclusão: Existe relação entre DM e HAS com a perda auditiva, tanto em adultos quanto em idosos. O comprometimento auditivo mostrou-se maior nos sujeitos que apresentavam DM e HAS associados, sugerindo um efeito sinérgico das duas doenças crônicas sobre a audição. A alteração auditiva do tipo neurossensorial prevaleceu.

OBJECTIVE:To present scientific evidence based on a systematic review of the literature (PRISMA), aiming to systematize evidence of the ototoxic effects of hydroxychloroquine (HCQ). METHODS:The studies were selected using a combination based on the Medical Subject Headings (MeSH). The databases searched were MEDLINE (PubMed), LILACS, SciELO, and BIREME, encompassing articles from January 2010 to May 2020, with no restrictions of language and place of publication.RESULTS: A total of 148 articles with the potential to be included were retrieved. Of these, two answered the research question, which consisted of seeking evidence of the ototoxic effects of hydroxychloroquine. These studies scored 11 in their quality assessment with the modified protocol by Pithon et al. 13 . CONCLUSIONS:The studies reported possible ototoxicity of HCQ. Audiovestibular changes, such as hearing loss, peripheral vestibular syndrome, and tinnitus were evidenced in patients submitted to HCQ. The improvement in the audiological examinations and the regression in the vestibular syndrome after stopping the treatment with HCQ are strong arguments in favor of the ototoxicity caused by this medication. However, there are still divergences about the relationship between ototoxic effects and the use of HCQ.

No abstract

No abstract