The present research has been car ried out with purpose of the reviewing the relation between job burnout and defense mechanisms used by air staff of Islamic Republic of Iran. The main hypothesis of this research is the presence of a relation between job burnout and defense mechanisms. In order to test the above hypothesis 234 subjects (137 male and 97 female) of air staff of Islamic Republic of Iran were selected by an available sampling. The device of the research is defense method questionnaire (Andrews) and Jackson and Maslach's professional fatigue questionnaire. After collecting questionnaires, analysis was done by using descriptive statistical methods, Pearson's correlation, multivariable regression analysis and independent T test about the obtained data. The results of this research after analyzing the data were obtained in a way that the people with grown defense mechanism have less affective burnout and it was identified that the more grown defense mechanism, the more individual success and the less individual success, the defense mechanisms are not grown. This research also shows that the defense mechanisms are not grown, they have more depersonalization.
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