Background: Viral meningitis is an inflammation of the leptomeninges as a manifestation of central nervous system (CNS) infection. More than 85% of viral meningitis cases are caused by non-polio enteroviruses. This is the first study on the description of the enteroviruses and the related serotypes involved in viral meningitis in Iran. Objectives: This project was conducted to improve our knowledge about the role of enteroviruses and their circulating serotypes in viral meningitis in Iran. Patients and Methods: Cerebrospinal fluids from 118 children under 13 years old with primary clinical diagnosis of aseptic meningitis were collected in Children Medical Center in Tehran and sent to Department of Virology of Pasteur Institute of Iran. To investigate the enteroviruses, 5`-noncoding regions were amplified by Real-Time PCR method using Pan-EV primers and a specific probe. Serotype identification in enterovirus positive samples was conducted by RT-PCR. Results: Enterovirus detection rate in all 118 Cerebrospinal fluid specimens was 10.16%. Most patients were 0 -2 years old (40.67%). Serotyping was achieved from 6 specimens with two polio viruses type 1 (vaccine type), two echoviruses 14, one echovirus 5 and one echovirus 30. Conclusions: Enteroviruses should be considered as the main cause of viral meningitis in Iran. Molecular detections of 5-'NCR and VP1-2A RT-PCR with sequence analysis were found to be better than the conventional methods, for direct diagnosis and EVs typing that may lead to decrease of the unnecessary hospitalizations.
Introduction: Mothers with a disabled child experience excessive stress, fatigue, frustration, and depression. Failure of mothers to effectively deal with these symptoms can lead to chronic fatigue and, in the long run, burnout. The objective of the present study was to determine the effect of supportive-training intervention on the burnout of mothers with disabled children. Methods: In this randomized controlled trial, 70 mothers with disabled children studying in special schools were selected in one of the urban areas of Iran. They were divided into two groups of intervention and control, using minimization random method. In the intervention group, mothers participated in supportive-training sessions once a week for a period of 6 weeks. The control group did not receive any special interventions. The data collection tool was a demographic data form and Shirom-Melamed Burnout Questionnaire (SMBQ). Burnout was evaluated as primary outcome at the beginning of the study and one month after the end of the intervention. The data were analyzed by SPSS software version 18. Results: Based on the results, there was no significant difference between the mean score of burnout in the intervention and control groups before the intervention. However, after the intervention, the mean score of burnout in the intervention group was significantly lower than that of the control group. Conclusion: Considering the positive effect of supportive-training intervention on the burnout of mothers of disabled children, this intervention is recommended by nurses and other health care providers in special schools, health centers, and supportive institutions.
Background and Aim: Sleep disorder is one of the most prevalent health problems among elderly people. Regular physical exercise can promote calmness. The current study aimed at comparing the effects of morning and evening walks on nighttime sleep quality among elderly people.
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